MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
In just over two decades since the discovery of the first microRNA (miRNA), the field of
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …
miRNA biology has expanded considerably. Insights into the roles of miRNAs in …
Transcriptional and post-transcriptional gene regulation by long non-coding RNA
Advances in genomics technology over recent years have led to the surprising discovery
that the genome is far more pervasively transcribed than was previously appreciated. Much …
that the genome is far more pervasively transcribed than was previously appreciated. Much …
Analyzing miRNA–lncRNA interactions
Long noncoding RNAs (lncRNAs) are noncoding transcripts usually longer than 200 nts that
have recently emerged as one of the largest and significantly diverse RNA families. The …
have recently emerged as one of the largest and significantly diverse RNA families. The …
DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts
Abstract microRNAs (miRNAs) are short non-coding RNAs (ncRNAs) that act as post-
transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs) …
transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs) …
Reexamining assumptions about miRNA-guided gene silencing
MicroRNAs (miRNAs) are short endogenously expressed RNAs that have the potential to
regulate the expression of any RNA. This potential has led to the publication of several …
regulate the expression of any RNA. This potential has led to the publication of several …
Clinical utility of circulating non-coding RNAs—an update
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …
The role of long noncoding RNAs in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the most frequent subtype of primary liver cancer and
one of the leading causes of cancer-related death worldwide. However, the molecular …
one of the leading causes of cancer-related death worldwide. However, the molecular …
A uniform system for the annotation of vertebrate microRNA genes and the evolution of the human microRNAome
Although microRNAs (miRNAs) are among the most intensively studied molecules of the
past 20 years, determining what is and what is not a miRNA has not been straightforward …
past 20 years, determining what is and what is not a miRNA has not been straightforward …
Noncoding RNA s in disease
E Lekka, J Hall - FEBS letters, 2018 - Wiley Online Library
Noncoding RNA s are emerging as potent and multifunctional regulators in all biological
processes. In parallel, a rapidly growing number of studies has unravelled associations …
processes. In parallel, a rapidly growing number of studies has unravelled associations …
Advances in CLIP technologies for studies of protein-RNA interactions
RNA binding proteins (RBPs) regulate all aspects in the life cycle of RNA molecules. To
elucidate the elements that guide RNA specificity, regulatory mechanisms, and functions of …
elucidate the elements that guide RNA specificity, regulatory mechanisms, and functions of …