Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal slee** time below the recommended ranges for health. Epidemiological and …

Circadian disruption, clock genes, and metabolic health

LA Schrader, SM Ronnekleiv-Kelly… - The Journal of Clinical …, 2024 - jci.org
A growing body of research has identified circadian-rhythm disruption as a risk factor for
metabolic health. However, the underlying biological basis remains complex, and complete …

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

H Sies, DP Jones - Nature reviews Molecular cell biology, 2020 - nature.com
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …

Circadian rhythms in neurodegenerative disorders

M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Circadian mechanisms in medicine

R Allada, J Bass - New England Journal of Medicine, 2021 - Mass Medical Soc
Circadian Mechanisms in Medicine Molecular insights into diurnal variations in human
physiology and behavior are extending our understanding of a wide range of disease …

Magnetic field effects in biology from the perspective of the radical pair mechanism

H Zadeh-Haghighi, C Simon - Journal of the Royal …, 2022 - royalsocietypublishing.org
Hundreds of studies have found that weak magnetic fields can significantly influence various
biological systems. However, the underlying mechanisms behind these phenomena remain …

Neuroinflammation, sleep, and circadian rhythms

MR Zielinski, AJ Gibbons - Frontiers in cellular and infection …, 2022 - frontiersin.org
Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa.
Sleep-inducing inflammatory molecules are activated by increased waking activity and …

[HTML][HTML] The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

JF Brooks, CL Behrendt, KA Ruhn, S Lee, P Raj… - Cell, 2021 - cell.com
Environmental light cycles entrain circadian feeding behaviors in animals that produce
rhythms in exposure to foodborne bacteria. Here, we show that the intestinal microbiota …

A photoregulatory mechanism of the circadian clock in Arabidopsis

X Wang, B Jiang, L Gu, Y Chen, M Mora, M Zhu… - Nature plants, 2021 - nature.com
Cryptochromes (CRYs) are photoreceptors that mediate light regulation of the circadian
clock in plants and animals. Here we show that CRYs mediate blue-light regulation of N6 …