Advancements in Gene Therapy for Human Disease: Trend of Current Clinical Trials
M Delshad, Z Davoodi-Moghaddam, M Khademi… - European Journal of …, 2024 - Elsevier
In an era of rapid scientific advancement, gene therapy has emerged as a groundbreaking
approach with the potential to revolutionize the treatment of a myriad of diseases and …
approach with the potential to revolutionize the treatment of a myriad of diseases and …
Gene therapy for deafness: we can do more
Y Chen, J Zhong, Y Shu - Nature Reviews Genetics, 2024 - nature.com
Challenges in the development of treatments for hereditary hearing loss include the
exploration of the underlying pathological mechanisms, the comprehensive evaluation of …
exploration of the underlying pathological mechanisms, the comprehensive evaluation of …
Affordable pricing of CRISPR treatments is a pressing ethical imperative
Casgevy, the world's first approved CRISPR-based cell therapy, has been priced at $2.2
million per patient. Although this hefty price tag was widely anticipated, the extremely high …
million per patient. Although this hefty price tag was widely anticipated, the extremely high …
In vivo engineering chimeric antigen receptor immune cells with emerging nanotechnologies
Adoptive cell therapy with chimeric antigen receptor (CAR) has revolutionized cancer
treatment in the past decade. Now several adoptive cell therapies are approved, and …
treatment in the past decade. Now several adoptive cell therapies are approved, and …
Clinical trials to gene therapy development and production in Brazil: a review
JAM Saute, V Picanço-Castro… - The Lancet Regional …, 2025 - thelancet.com
Challenges related to the implementation of gene therapy products are daunting for low-to
middle-income countries, such as Brazil, and include the creation of an appropriate …
middle-income countries, such as Brazil, and include the creation of an appropriate …
Sickle cell disease in India: the journey and hope for the future
K Gupta, L Krishnamurti, D Jain - Hematology, 2024 - ashpublications.org
India, the most populous nation in the world, also has a high frequency of the sickle
hemoglobin (HbS) allele globally. The Arab Indian HbS haplotype in India is characterized …
hemoglobin (HbS) allele globally. The Arab Indian HbS haplotype in India is characterized …
Strengthening advanced therapy for sickle cell disease in Africa: experience from sickle cell disease centre in Dar es Salaam, Tanzania
D Bukini, A Rifai, C Kanza, F Luoga, D Maingu… - BMJ Global …, 2025 - gh.bmj.com
Despite progress in healthcare services for individuals living with sickle cell disease (SCD)
in Africa, substantial gaps remain in advanced treatments for SCD. To help address this …
in Africa, substantial gaps remain in advanced treatments for SCD. To help address this …
[HTML][HTML] Efficient manufacturing of CAR-T cells from whole blood: a scalable approach to reduce costs and enhance accessibility in cancer therapy
R Traynor, I Vignola, S Sarkar, M Prochazkova, Y Cai… - Cytotherapy, 2024 - Elsevier
Background Chimeric antigen receptor T (CAR-T) cells have significantly advanced the
treatment of cancers such as leukemia and lymphoma. Traditionally, T cells are collected …
treatment of cancers such as leukemia and lymphoma. Traditionally, T cells are collected …
Affordable pricing of CRISPR treatments is a pressing ethical imperative
J Rueda Etxebarria, Í Miguel Beriain, L Montoliu - 2024 - digibug.ugr.es
Casgevy, the world's first approved CRISPR-based cell therapy, has been priced at $2.2
million per patient. Although this hefty price tag was widely anticipated, the extremely high …
million per patient. Although this hefty price tag was widely anticipated, the extremely high …
[PDF][PDF] The future of precision medicine: Integrating genetic engineering into pharmacological research
MM Hossen - 2025 - genesispcl.com
The integration of genetic engineering into pharmacological research is transforming the
landscape of precision medicine, offering the potential to revolutionize healthcare. Precision …
landscape of precision medicine, offering the potential to revolutionize healthcare. Precision …