MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

The molecular mechanisms operating in human organ transplant rejection are best inferred
from the mRNAs expressed in biopsies because the corresponding proteins often have low …

This meeting report from the XV Banff conference describes the creation of a multiorgan
transplant gene panel by the Banff Molecular Diagnostics Working Group (MDWG). This …

Progress in renal transplantation requires improved understanding and assessment of
rejection and injury. Study of the relationship between gene expression and clinical …

Invasive graft biopsies assess the efficacy of immunosuppression through lagging indicators
of transplant rejection. We report on a microporous scaffold implant as a minimally invasive …

MicroRNAs are epigenetic regulators of gene expression at the posttranscriptional level.
They are involved in intercellular communication and crosstalk between different organs. As …

Introduction Acute rejection (AR) continues to be a significant obstacle for short-and long-
term graft survival in kidney transplant recipients. Herein, we aimed to examine urinary …

The control of gene expression by microRNAs (miRNAs, miR) influences many cellular
functions, including cellular differentiation, cell proliferation, cell development, and functional …

Graft endothelial cell (EC) injury is central to the pathogenesis of antibody-mediated
rejection (AMR). The ability of donor-specific antibodies (DSA) to bind C1q and activate the …

BACKGROUND Acute cellular rejection (ACR) is a major complication in heart
transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of …