TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Factor XIII: a coagulation factor with multiple plasmatic and cellular functions

L Muszbek, Z Bereczky, Z Bagoly… - Physiological …, 2011 - journals.physiology.org
Factor XIII (FXIII) is unique among clotting factors for a number of reasons: 1) it is a
protransglutaminase, which becomes activated in the last stage of coagulation; 2) it works …

Seeking health information online: does Wikipedia matter?

MR Laurent, TJ Vickers - Journal of the American Medical …, 2009 - academic.oup.com
Objective: To determine the significance of the English Wikipedia as a source of online
health information. Design: The authors measured Wikipedia's ranking on general Internet …

[HTML][HTML] Factor XIII: novel structural and functional aspects

I Komaromi, Z Bagoly, L Muszbek - Journal of Thrombosis and Haemostasis, 2011 - Elsevier
Factor (F) XIII is a protransglutaminase that, in addition to maintaining hemostasis, has
multiple plasmatic and intracellular functions. Its plasmatic form (pFXIII) is a tetramer of two …

[HTML][HTML] Biocatalysis by transglutaminases: a review of biotechnological applications

MP Savoca, E Tonoli, AG Atobatele, EAM Verderio - Micromachines, 2018 - mdpi.com
The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent
isopeptide bonds (crosslinks) between peptide-bound glutamine and lysine residues, but …

Transglutaminase 2: a multi-functional protein in multiple subcellular compartments

D Park, SS Choi, KS Ha - Amino acids, 2010 - Springer
Abstract Transglutaminase 2 (TG2) is a multifunctional protein that can function as a
transglutaminase, G protein, kinase, protein disulfide isomerase, and as an adaptor protein …

Genetic landscape in coagulation factor XIII associated defects–Advances in coagulation and beyond

H Javed, S Singh, SUR Urs, J Oldenburg, A Biswas - Blood reviews, 2023 - Elsevier
Coagulation factor XIII (FXIII) acts as a fine fulcrum in blood plasma that maintains the
balance between bleeding and thrombosis by covalently crosslinking the pre-formed fibrin …

Coagulation factor XIIIa substrates in human plasma: identification and incorporation into the clot

CL Nikolajsen, TF Dyrlund, ET Poulsen… - Journal of Biological …, 2014 - jbc.org
Coagulation factor XIII (FXIII) is a transglutaminase with a well defined role in the final stages
of blood coagulation. Active FXIII (FXIIIa) catalyzes the formation of ϵ-(γ-glutamyl) lysine …

Biological functionalities of transglutaminase 2 and the possibility of its compensation by other members of the transglutaminase family

BO Odii, P Coussons - The scientific world journal, 2014 - Wiley Online Library
Transglutaminase 2 (TG2) is the most widely distributed and most abundantly expressed
member of the transglutaminase family of enzymes, a group of intracellular and extracellular …

Physiological, pathological, and structural implications of non-enzymatic protein–protein interactions of the multifunctional human transglutaminase 2

K Kanchan, M Fuxreiter, L Fésüs - Cellular and Molecular Life Sciences, 2015 - Springer
Abstract Transglutaminase 2 (TG2) is a ubiquitously expressed member of an enzyme family
catalyzing Ca 2+-dependent transamidation of proteins. It is a multifunctional protein having …