First-in-pediatrics phase I study of crenolanib besylate (CP-868,596-26) administered during...

Turnitin 降AI改写 早检测系统 早降重系统 Turnitin-UK版 万方检测-期刊版 维普编辑部版 Grammarly检测 Paperpass检测 checkpass检测 PaperYY检测

CAR T-cells targeting FLT3 have potent activity against FLT3−ITD+ AML and act synergistically with the FLT3-inhibitor crenolanib

H Jetani, I Garcia-Cadenas, T Nerreter, S Thomas… - Leukemia, 2018 - nature.com
FMS-like tyrosine kinase 3 (FLT3) is a transmembrane protein expressed on normal
hematopoietic stem and progenitor cells (HSC) and retained on malignant blasts in acute …
保存 引用 被引用数: 196 関連記事 全 6 バージョン
[Free GPT-4]
[DeepSeek]
[PDF] frontiersin.org

Invaders Exposed: Understanding and Targeting Tumor Cell Invasion in Diffuse Intrinsic Pontine Glioma

TA Kluiver, M Alieva, DG Van Vuurden… - Frontiers in …, 2020 - frontiersin.org
Diffuse Intrinsic Pontine Glioma (DIPG) is a rare, highly aggressive pediatric brain tumor that
originates in the pons. DIPG is untreatable and universally fatal, with a median life …
保存 引用 被引用数: 37 関連記事 全 7 バージョン キャッシュ
[Free GPT-4]
[DeepSeek]
[PDF] frontiersin.org

Targeting FLT3 signaling in childhood acute myeloid leukemia

AN Sexauer, SK Tasian - Frontiers in pediatrics, 2017 - frontiersin.org
Acute myeloid leukemia (AML) is the second most common leukemia of childhood and is
associated with high rates of chemotherapy resistance and relapse. Clinical outcomes for …
保存 引用 被引用数: 48 関連記事 全 8 バージョン キャッシュ
[Free GPT-4]
[DeepSeek]
[PDF] nih.gov

The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant …

TJ Mathias, K Natarajan, S Shukla, KA Doshi… - Investigational new …, 2015 - Springer
Summary Background Crenolanib (crenolanib besylate, 4-piperidinamine, 1-[2-[5-[(3-methyl-
3-oxetanyl) methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-, monobenzenesulfonate) is a …
保存 引用 被引用数: 29 関連記事 全 5 バージョン
[Free GPT-4]
[DeepSeek]
[PDF] nih.gov

Management of diffuse intrinsic pontine glioma in children: current and future strategies for improving prognosis

EC Kaye, JN Baker, A Broniscer - CNS oncology, 2014 - Taylor & Francis
Diffuse intrinsic pontine glioma (DIPG) is one of the deadliest pediatric central nervous
system cancers in spite of treatment with radiation therapy, the current standard of care. The …
保存 引用 被引用数: 31 関連記事 全 5 バージョン
[Free GPT-4]
[DeepSeek]
[PDF] nih.gov

Radiation dose response of neurologic symptoms during conformal radiotherapy for diffuse intrinsic pontine glioma

CL Tinkle, K Campbell, Y Han, Y Li, B Bianski… - Journal of Neuro …, 2020 - Springer
Purpose To estimate the rate and magnitude of neurologic symptom change during radiation
therapy (RT) and impact of symptom change on survival outcomes in patients with diffuse …
保存 引用 被引用数: 13 関連記事 全 6 バージョン
[Free GPT-4]
[DeepSeek]
[PDF] nih.gov

Defining optimal target volumes of conformal radiation therapy for diffuse intrinsic pontine glioma

CL Tinkle, B Simone, J Chiang, X Li, K Campbell… - International Journal of …, 2020 - Elsevier
Purpose Optimal radiation therapy (RT) target margins for diffuse intrinsic pontine glioma
(DIPG) are unknown. We sought to define disease progression patterns in a contemporary …
保存 引用 被引用数: 12 関連記事 全 5 バージョン

Use of flt3 car-t cells and flt3 inhibitors to treat acute myeloid leukemia

M Hudecek, H Jetani - US Patent App. 18/145,837, 2023 - Google Patents
US20230277591A1 - Use of flt3 car-t cells and flt3 inhibitors to treat acute myeloid leukemia
- Google Patents US20230277591A1 - Use of flt3 car-t cells and flt3 inhibitors to treat acute …
保存 引用 被引用数: 1 関連記事 全 2 バージョン キャッシュ
[Free GPT-4]
[DeepSeek]
[PDF] googleapis.com

Use of flt3 car-t cells and flt3 inhibitors to treat acute myeloid leukemia

M Hudecek, H Jetani - US Patent App. 16/633,132, 2020 - Google Patents
US20200206266A1 - Use of flt3 car-t cells and flt3 inhibitors to treat acute myeloid leukemia
- Google Patents US20200206266A1 - Use of flt3 car-t cells and flt3 inhibitors to treat acute …
保存 引用 関連記事 全 2 バージョン キャッシュ