Multistability is ubiquitous in nature. From a mathematical point of view, multistability is the
coexistence of stable states (attractors) for the same set of system parameters. The …

A distributed biological system can be defined as a system whose components are located
in different subpopulations, which communicate and coordinate their actions through …

Growth-mediated feedback between synthetic gene circuits and host organisms leads to
diverse emerged behaviors, including growth bistability and enhanced ultrasensitivity …

Here, we adapted the basic concept of artificial neural networks (ANNs) and experimentally
demonstrate a broadly applicable single layer ANN type architecture with molecular …

Escherichia coli is a common chassis for synthetic gene circuit studies. In addition to the
dose–response of synthetic gene circuits, the analysis of dynamic responses is also an …

Mitochondrial permeability transition pore (PTP), a key regulator of cell life and death
processes, is triggered by calcium ions (Ca 2+) and potentiated by reactive oxygen species …

Phase variation, which causes splitting the homogeneous bacterial population into
subpopulations of the cells with different and reversible activity of the same variable genes …

Cooperative protein–protein and protein–DNA interactions form programmable complex
assemblies, often performing non-linear gene regulatory operations involved in signal …

While the vision of synthetic biology is to create complex genetic systems in a rational
fashion, system-level behaviors are often perplexing due to the context-dependent dynamics …

In epithelial-mesenchymal transition (EMT), cells organized into sheets break away and
become motile mesenchymal cells. EMT plays a crucial role in wound healing, embryonic …