Chronic non-healing wounds have become a major worldwide healthcare burden. The
impact of biofilms on chronic wound infection is well established. Despite increasing …

The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

The skin microbiota is intimately coupled with cutaneous health and disease. Interactions
between commensal microbiota and the multiple cell types involved in cutaneous wound …

Microbial biofilms are formed by adherence of the bacteria through their secreted polymer
matrices. The major constituents of the polymer matrices are extracellular DNAs, proteins …

Significance: Keratinocytes, a major cellular component of the epidermis, are responsible for
restoring the epidermis after injury through a process termed epithelialization. This review …

Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Interest in the role of the microbiome in human health has burgeoned over the past decade
with the advent of new technologies for interrogating complex microbial communities. The …

Background: Despite a growing consensus that biofilms contribute to a delay in the healing
of chronic wounds, conflicting evidence pertaining to their identification and management …

As the prevalence of diabetes is increasing globally, secondary complications associated to
this endocrinal disorder are also ascending. Diabetic foot ulcers are potentially modifying …

The skin is the human body's largest organ, colonized by a diverse milieu of
microorganisms, most of which are harmless or even beneficial to their host. Colonization is …