Prognostic and predictive biomarkers in gliomas

P Śledzińska, MG Bebyn, J Furtak… - International journal of …, 2021 - mdpi.com
Gliomas are the most common central nervous system tumors. New technologies, including
genetic research and advanced statistical methods, revolutionize the therapeutic approach …

The role of proteoglycans in cancer metastasis and circulating tumor cell analysis

TD Ahrens, SR Bang-Christensen… - Frontiers in cell and …, 2020 - frontiersin.org
Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw.
They represent not only the primary tumor site, but also potential metastatic lesions, and …

Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate

EE Vidal-Calvo, A Martin-Salazar, S Choudhary… - Nature …, 2024 - nature.com
Molecular similarities between embryonic and malignant cells can be exploited to target
tumors through specific signatures absent in healthy adult tissues. One such embryonic …

Detection and clinical significance of circulating tumor cells in colorectal cancer

M Jiang, S **, J Han, T Li, J Shi, Q Zhong, W Li… - Biomarker …, 2021 - Springer
Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal
cancer (CRC). However, biopsy is an invasive method, and due to the temporal and spatial …

Circulating tumor cells as predictive and prognostic biomarkers in solid tumors

M Capuozzo, F Ferrara, M Santorsola, A Zovi… - Cells, 2023 - mdpi.com
Circulating tumor cells (CTCs) have emerged as pivotal biomarkers with significant
predictive and prognostic implications in solid tumors. Their presence in peripheral blood …

Circulating liquid biopsy biomarkers in Glioblastoma: advances and challenges

AA Seyhan - International Journal of Molecular Sciences, 2024 - pmc.ncbi.nlm.nih.gov
Gliomas, particularly glioblastoma (GBM), represent the most prevalent and aggressive
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Blood-based biomarkers for glioma in the context of gliomagenesis: a systematic review

H Ali, R Harting, R de Vries, M Ali, T Wurdinger… - Frontiers in …, 2021 - frontiersin.org
Background Gliomas are the most common and aggressive tumors of the central nervous
system. A robust and widely used blood-based biomarker for glioma has not yet been …

Preoperative diagnosis and molecular characterization of gliomas with liquid biopsy and radiogenomics

C Balana, S Castañer, C Carrato, T Moran… - Frontiers in …, 2022 - frontiersin.org
Gliomas are a heterogenous group of central nervous system tumors with different outcomes
and different therapeutic needs. Glioblastoma, the most common subtype in adults, has a …

Establishment and validation of a plasma oncofetal chondroitin sulfated proteoglycan for pan-cancer detection

PF Zhang, ZY Wu, WB Zhang, YQ He, K Chen… - Nature …, 2023 - nature.com
Various biomarkers targeting cell-free DNA (cfDNA) and circulating proteins have been
tested for pan-cancer detection. Oncofetal chondroitin sulfate (ofCS), which distinctively …