The global production of plastics has continuously been soaring over the last decades due
to their extensive use in our daily life and in industries. Although synthetic plastics offer great …

Viruses have coevolved with their hosts, acquiring strategies to subvert host cellular
pathways for effective viral replication and spread. Human cytomegalovirus (HCMV), a …

Although many organisms capture or respond to sunlight, few enzymes are known to be
driven by light. Among these are DNA photolyases and the photosynthetic reaction centers …

Reversible detyrosination of α-tubulin is crucial to microtubule dynamics and functions, and
defects have been implicated in cancer, brain disorganization, and cardiomyopathies. The …

Despite its size and rigidity, the cell nucleus can be moved or reorganized by cytoskeletal
filaments under various conditions (for example, during viral infection),,,,,,,,,–. Moreover …

Nuclear replication of cytomegalovirus relies on elaborate mechanisms of
nucleocytoplasmic egress of viral particles. Thus, the role of two essential and conserved …

Most DNA viruses replicate in the nucleus and exit it either by passing through the nuclear
pores or by rupturing the nuclear envelope. Unusually, herpesviruses have evolved a …

Human cytomegalovirus (HCMV) expresses a variety of viral regulatory proteins that
undergo close interaction with host factors including viral-cellular multiprotein complexes …

Generation of dimers, trimers and dendrimers of bioactive compounds is an approach that
has recently been developed for the discovery of new potent drug candidates. Herein, we …

Endoplasmic reticulum (ER) aminopeptidases ERAP1 and ERAP2 (ERAPs) are crucial
enzymes sha** the major histocompatibility complex I (MHC I) immunopeptidome. In the …