Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

Tumor progression involves the ability of cancer cells to communicate with each other and
with neighboring normal cells in their microenvironment. Microvesicles (MV) derived from …

Purpose The role of the microenvironment during the initiation and progression of
carcinogenesis is now realized to be of critical importance, both for enhanced understanding …

Transglutaminase 2 (TG2 or tissue transglutaminase) is a highly complex multifunctional
protein that acts as transglutaminase, GTPase/ATPase, protein disulfide isomerase, and …

Transglutaminase 2 (TG2) is the most widely distributed member of the transglutaminase
family with almost all cell types in the body expressing TG2 to varying extents. In addition to …

Dynamic interactions between organelles are responsible for a variety of intercellular
functions, and the endoplasmic reticulum (ER)–mitochondrial axis is recognized as a …

Tissue transglutaminase (TG2) is a ubiquitously expressed member of the transglutaminase
family of Ca2+‐dependent crosslinking enzymes. Unlike other family members, TG2 is a …

Abstract Transglutaminase 2 (TG2) is primarily known as the most ubiquitously expressed
member of the transglutaminase family with Ca 2+-dependent protein crosslinking activity; …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a deadly progressive disease with few
treatment options. Transglutaminase 2 (TG2) is a multifunctional protein, but its function in …