The gut microbiome in Alzheimer's disease: what we know and what remains to be explored

S Chandra, SS Sisodia, RJ Vassar - Molecular neurodegeneration, 2023 - Springer
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

Recent advancements in pathogenesis, diagnostics and treatment of Alzheimer's disease

S Khan, KH Barve, MS Kumar - Current neuropharmacology, 2020 - benthamdirect.com
Background: The only conclusive way to diagnose Alzheimer's is to carry out brain autopsy
of the patient's brain tissue and ascertain whether the subject had Alzheimer's or any other …

Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment

S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …

The progress of gut microbiome research related to brain disorders

S Zhu, Y Jiang, K Xu, M Cui, W Ye, G Zhao… - Journal of …, 2020 - Springer
There is increasing evidence showing that the dynamic changes in the gut microbiota can
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …

Antibiotics, gut microbiota, and Alzheimer's disease

F Angelucci, K Cechova, J Amlerova, J Hort - Journal of neuroinflammation, 2019 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease whose various pathophysiological
aspects are still being investigated. Recently, it has been hypothesized that AD may be …

Short-chain fatty acids and human health: from metabolic pathways to current therapeutic implications

S Facchin, L Bertin, E Bonazzi, G Lorenzon… - Life, 2024 - mdpi.com
The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as
the gut microbiota, which play a pivotal role in breaking down undigested foods, such as …

[HTML][HTML] Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases

C Gubert, G Kong, T Renoir, AJ Hannan - Neurobiology of disease, 2020 - Elsevier
The last decade has witnessed an exponentially growing interest in gut microbiota and the
gut-brain axis in health and disease. Accumulating evidence from preclinical and clinical …

[HTML][HTML] Physical exercise inhibits inflammation and microglial activation

O Mee-Inta, ZW Zhao, YM Kuo - Cells, 2019 - mdpi.com
Accumulating evidence indicates that exercise can enhance brain function and attenuate
neurodegeneration. Besides improving neuroplasticity by altering the synaptic structure and …

Probiotics for Alzheimer's disease: A systematic review

R Naomi, H Embong, F Othman, HF Ghazi, N Maruthey… - Nutrients, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders affecting
mostly the elderly. It is characterized by the presence of Aβ and neurofibrillary tangles (NFT) …

Emerging role of gut microbiota dysbiosis in neuroinflammation and neurodegeneration

R Solanki, A Karande, P Ranganathan - Frontiers in Neurology, 2023 - frontiersin.org
Alzheimer's disease (AD), is a chronic age-related progressive neurodegenerative disorder,
characterized by neuroinflammation and extracellular aggregation of Aβ peptide …