In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …

Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead
to cirrhosis, cancer, and liver failure. Liver cancer is the third leading cause of cancer …

Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

Simple Summary Hepatocellular carcinoma (HCC) is a global health challenge. Hepatitis
virus infection (including HBV, HCV and HDV) is one of the major risk factors for HCC …

Genetic alterations affecting transforming growth factor–β (TGF-β) signaling are
exceptionally common in diseases and cancers of the gastrointestinal system. As a regulator …

MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …

During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …

Hepatitis B virus (HBV) is DNA-based virus, member of the Hepadnaviridae family, which
can cause liver disease and increased risk of hepatocellular carcinoma (HCC) in infected …

The liver constitutes the largest gland in the human body and performs many different
functions. It processes what a person eats and drinks and converts food into nutrients that …

The nonsteroidal anti‐inflammatory drugs (NSAIDs) are commonly prescribed by medical
practitioners in many clinical conditions for the symptomatic treatment of pain and fever. Due …