[HTML][HTML] Mechanisms of long COVID and the path toward therapeutics

MJ Peluso, SG Deeks - Cell, 2024 - cell.com
Long COVID, a type of post-acute sequelae of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)(PASC) defined by medically unexplained symptoms following …

Silent battles: immune responses in asymptomatic SARS-CoV-2 infection

N Le Bert, T Samandari - Cellular & Molecular Immunology, 2024 - nature.com
SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice

RP dos Santos Alves, J Timis, R Miller… - Nature …, 2024 - nature.com
Abstract SARS-CoV-2-reactive T cells are detected in some healthy unexposed individuals.
Human studies indicate these T cells could be elicited by the common cold coronavirus …

Map** the immunopeptidome of seven SARS-CoV-2 antigens across common HLA haplotypes

A Braun, LC Rowntree, Z Huang, K Pandey… - Nature …, 2024 - nature.com
Most COVID-19 vaccines elicit immunity against the SARS-CoV-2 Spike protein. However,
Spike protein mutations in emerging strains and immune evasion by the SARS-CoV-2 virus …

Biomarkers of transfusion transmitted occult hepatitis B virus infection: Where are we and what next?

MX Fu, P Simmonds, M Andersson… - Reviews in Medical …, 2024 - Wiley Online Library
Blood transfusion is a vital procedure, where transfusion‐transmitted infection of hepatitis B
virus (HBV) remains an important issue, especially from blood donors with occult hepatitis B …

The eye of the storm: investigating the long-term cardiovascular effects of COVID-19 and variants

N Vishwakarma, RB Goud, MP Tirupattur, LC Katwa - Cells, 2023 - mdpi.com
COVID-19 had stormed through the world in early March of 2019, and on 5 May 2023, SARS-
CoV-2 was officially declared to no longer be a global health emergency. The rise of new …

The binding profile of SARS‐CoV‐2 with human leukocyte antigen polymorphisms reveals critical alleles involved in immune evasion

Y Zhan, L Ye, Q Ouyang, J Yin, J Cui… - Journal of Medical …, 2023 - Wiley Online Library
The COVID‐19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2), astonished the world and led to millions of deaths. Due to viral new …

The Influence of Cross-Reactive T Cells in COVID-19

PJ Eggenhuizen, JD Ooi - Biomedicines, 2024 - mdpi.com
Memory T cells form from the adaptive immune response to historic infections or
vaccinations. Some memory T cells have the potential to recognise unrelated pathogens like …