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Neuroinflammation as a common feature of neurodegenerative disorders
Neurodegenerative diseases share the fact that they derive from altered proteins that
undergo an unfolding process followed by formation of β-structures and a pathological …
undergo an unfolding process followed by formation of β-structures and a pathological …
MicroRNA delivery through nanoparticles
MicroRNAs (miRNAs) are attracting a growing interest in the scientific community due to
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
their central role in the etiology of major diseases. On the other hand, nanoparticle carriers …
Systematic review of miRNA as biomarkers in Alzheimer's disease
Currently there are 850,000 people with Alzheimer's disease in the UK, with an estimated
rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of …
rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of …
[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
Deregulated mitochondrial microRNAs in Alzheimer's disease: focus on synapse and mitochondria
Alzheimer's disease (AD) is the most common cause of dementia and is currently one of the
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …
[HTML][HTML] Epigenetics of Alzheimer's disease
There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …
Perinatal and early-life nutrition, epigenetics, and allergy
Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …
prevalence of allergic diseases over the last several decades. Environmental triggers …
The epigenetics of aging and neurodegeneration
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …
expression that do not involve changes in the genotype. Epigenetics is of increasing …
Astrogliosis: an integral player in the pathogenesis of Alzheimer's disease
Alzheimer's disease is the main cause of dementia in the elderly and begins with a subtle
decline in episodic memory followed by a more general decline in overall cognitive abilities …
decline in episodic memory followed by a more general decline in overall cognitive abilities …
The pervasive role of the miR-181 family in development, neurodegeneration, and cancer
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
regulation of gene expression. Evidence accumulating in the past decades indicate that they …