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Mitochondria in disease: changes in shapes and dynamics
Mitochondrial structure often determines the function of these highly dynamic,
multifunctional, eukaryotic organelles, which are essential for maintaining cellular health …
multifunctional, eukaryotic organelles, which are essential for maintaining cellular health …
[HTML][HTML] Mitophagy in human diseases
L Doblado, C Lueck, C Rey, AK Samhan-Arias… - International journal of …, 2021 - mdpi.com
Mitophagy is a selective autophagic process, essential for cellular homeostasis, that
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …
eliminates dysfunctional mitochondria. Activated by inner membrane depolarization, it plays …
[HTML][HTML] The role of mitochondria in amyotrophic lateral sclerosis
Mitochondria are unique organelles that are essential for a variety of cellular processes
including energy metabolism, calcium homeostasis, lipid biosynthesis, and apoptosis …
including energy metabolism, calcium homeostasis, lipid biosynthesis, and apoptosis …
Mitochondrial fission protein 1: emerging roles in organellar form and function in health and disease
Mitochondrial fission protein 1 (Fis1) was identified in yeast as being essential for
mitochondrial division or fission and subsequently determined to mediate human …
mitochondrial division or fission and subsequently determined to mediate human …
Three-dimensional ultrastructure of giant mitochondria in human non-alcoholic fatty liver disease
Giant mitochondria are peculiarly shaped, extremely large mitochondria in hepatic
parenchymal cells, the internal structure of which is characterised by atypically arranged …
parenchymal cells, the internal structure of which is characterised by atypically arranged …
Mitochondria in aging and Alzheimer's disease: Focus on mitophagy
Alzheimer's disease (AD) is characterized by the accumulation of amyloid β and
phosphorylated τ protein aggregates in the brain, which leads to the loss of neurons. Under …
phosphorylated τ protein aggregates in the brain, which leads to the loss of neurons. Under …
Placental mitochondrial function and dysfunction in preeclampsia
The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …
Increased mitochondrial fusion allows the survival of older animals in diverse C. elegans longevity pathways
Mitochondria are dynamic organelles that undergo fusion and fission events. Mitochondrial
dynamics are required for mitochondrial viability and for responses to changes in …
dynamics are required for mitochondrial viability and for responses to changes in …
Mitochondrial dysfunction contributes to the pathogenesis of Alzheimer's disease
FA Cabezas-Opazo, K Vergara-Pulgar… - Oxidative medicine …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disease that affects millions of people
worldwide. Currently, there is no effective treatment for AD, which indicates the necessity to …
worldwide. Currently, there is no effective treatment for AD, which indicates the necessity to …
Effect of Ambient PM2.5 on Lung Mitochondrial Damage and Fusion/Fission Gene Expression in Rats
R Li, X Kou, H Geng, J **e, Z Yang… - Chemical research in …, 2015 - ACS Publications
Exposure to ambient fine particulate matter (PM2. 5) increases the risk of respiratory
disease. Although previous mitochondrial research has provided new information about PM …
disease. Although previous mitochondrial research has provided new information about PM …