Rise and fall of therapeutic hypothermia in low-resource settings: lessons from the HELIX trial

V Krishnan, V Kumar, S Shankaran… - Indian Journal of Pediatrics, 2021 - Springer
In the past decade, therapeutic hypothermia using a variety of low-cost devices has been
widely implemented in India and other low-and middle-income countries (LMIC) without …

Incidence and outcomes of intrapartum-related neonatal encephalopathy in low-income and middle-income countries: a systematic review and meta-analysis

AJ Kukka, S Waheddoost, N Brown, H Litorp… - BMJ Global …, 2022 - gh.bmj.com
Aim To examine the incidence of intrapartum-related neonatal encephalopathy, and
neonatal mortality and neurodevelopmental outcomes associated with it in low-income and …

Review of a frugal cooling mattress to induce therapeutic hypothermia for treatment of hypoxic-ischaemic encephalopathy in the UK NHS

G Dallera, M Skopec, C Battersby, J Barlow… - Globalization and …, 2022 - Springer
Hypoxic ischaemic encephalopathy (HIE) is a major cause of neonatal mortality and
disability in the United Kingdom (UK) and has significant human and financial costs …

Therapeutic hypothermia for neonatal hypoxic-ischaemic encephalopathy in India (THIN study): a randomised controlled trial

K Aker, R Støen, L Eikenes, M Martinez-Biarge… - Archives of Disease in …, 2020 - fn.bmj.com
Objective To evaluate the neuroprotective effect of therapeutic hypothermia (TH) induced by
phase changing material (PCM) on MRI biomarkers in infants with hypoxic-ischaemic …

Effect of therapeutic hypothermia on the outcome in term neonates with hypoxic ischemic encephalopathy—a randomized controlled trial

RC Catherine, VB Ballambattu… - Journal of Tropical …, 2021 - academic.oup.com
Objective To assess the effect of therapeutic hypothermia on the outcome in term neonates
with hypoxic ischemic encephalopathy (HIE). Methods A randomized controlled trial was …

Cooling during transportation of newborns with hypoxic ischemic encephalopathy using phase change material mattresses in low-resource settings: a randomized …

HTT Tran, DM Tran, HT Le, L Hellström-Westas… - BMC pediatrics, 2024 - Springer
Objective To determine the effectiveness of phase-change-material mattress (PCM) during
transportation of newborns with hypoxic ischemic encephalopathy (HIE). Study design …

Hypothermia for encephalopathy in low-income and middle-income countries: feasibility of whole-body cooling using a low-cost servo-controlled device

V Oliveira, JR Kumutha, E Narayanan… - BMJ paediatrics …, 2018 - pmc.ncbi.nlm.nih.gov
Although therapeutic hypothermia (TH) is the standard of care for hypoxic ischaemic
encephalopathy in high-income countries, the safety and efficacy of this therapy in low …

Magnesium sulfate as an adjunct to therapeutic hypothermia in the management of term infants with hypoxic–ischemic encephalopathy: A randomized, parallel-group …

C Kumar, B Adhisivam, Z Bobby, BV Bhat - Indian Journal of Pediatrics, 2023 - Springer
Objective To evaluate whether magnesium sulfate and therapeutic hypothermia in
combination decreases mortality and/or major neurodevelopmental disability at 1 y of age …

Neuronal biomarkers in predicting neurodevelopmental outcome in term babies with perinatal asphyxia

RC Catherine, BV Bhat, B Adhisivam… - The Indian Journal of …, 2020 - Springer
Objective To assess whether serum levels of neuronal biomarkers (S100 calcium-binding
protein B and Neuron specific enolase) correlate with the neurodevelopmental outcome of …

Phase-changing glauber salt solution for medical applications in the 28–32 C interval

L Olson, C Lothian, U Ådén, H Lagercrantz… - Materials, 2021 - mdpi.com
(1) Background: The field of medicine requires simple cooling materials. However, there is
little knowledge documented about phase change materials (PCM) covering the range of 28 …