The choroid plexus: a missing link in our understanding of brain development and function

NR Saunders, KM Dziegielewska… - Physiological …, 2023 - journals.physiology.org
Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier,
despite a much longer history. This review has two overall aims. The first is to outline long …

Risk of major congenital malformations and exposure to antiseizure medication monotherapy

D Battino, T Tomson, E Bonizzoni, J Craig… - JAMA …, 2024 - jamanetwork.com
Importance Women with epilepsy (WWE) require treatment with antiseizure medications
(ASMs) during pregnancy, which may be associated with an increased risk of major …

Association of prenatal exposure to antiseizure medication with risk of autism and intellectual disability

MH Bjørk, H Zoega, MK Leinonen, JM Cohen… - JAMA …, 2022 - jamanetwork.com
Importance Women with epilepsy frequently need antiseizure medication (ASM) to prevent
seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure to …

Management of anti-seizure medications during pregnancy: advancements in the past decade

C Avachat, JM Barry, X Lyu, CM Sherwin, AK Birnbaum - Pharmaceutics, 2022 - mdpi.com
Management of seizures often involves continuous medication use throughout a patient's
life, including when a patient is pregnant. The physiological changes during pregnancy can …

Prenatal exposure to antiseizure medication and incidence of childhood-and adolescence-onset psychiatric disorders

JW Dreier, MH Bjørk, S Alvestad, M Gissler… - JAMA …, 2023 - jamanetwork.com
Importance Prenatal antiseizure medication (ASM) exposure has been associated with
adverse early neurodevelopment, but associations with a wider range of psychiatric end …

Comparative safety of antiseizure medication monotherapy for major malformations

JM Cohen, S Alvestad, CE Cesta, MH Bjørk… - Annals of …, 2023 - Wiley Online Library
Objective This study was undertaken to examine the comparative safety of antiseizure
medication (ASM) monotherapy in pregnancy with respect to risk of major congenital …

Risk of perinatal and maternal morbidity and mortality among pregnant women with epilepsy

N Razaz, J Igland, MH Bjørk, KS Joseph… - JAMA …, 2024 - jamanetwork.com
Importance Maternal epilepsy is associated with adverse pregnancy and neonatal
outcomes. A better understanding of this condition and the associated risk of mortality and …

Trends and patterns of antiseizure medication prescribing during pregnancy between 1995 and 2018 in the United kingdom: a cohort study

P Madley‐Dowd, J Rast, VH Ahlqvist… - … Journal of Obstetrics …, 2024 - Wiley Online Library
Objective To examine antiseizure medication (ASM) prescription during pregnancy. Design
Population‐based drug utilisation study. Setting UK primary and secondary care data, 1995 …

Patterns of prescription medication use during the first trimester of pregnancy in the United States, 1997–2018

MM Werler, SM Kerr, EC Ailes… - Clinical …, 2023 - Wiley Online Library
The objective of this analysis was to describe patterns of prescription medication use during
pregnancy, including secular trends, with consideration of indication, and distributions of use …

[HTML][HTML] Malformation risk of new anti-epileptic drugs in women with epilepsy; observational data from the Kerala registry of epilepsy and pregnancy (KREP)

SV Thomas, P Jeemon, R Pillai, M Jose… - Seizure, 2021 - Elsevier
Objectives: We aim to report the major congenital malformation (MCM) rates for new and old
anti-epileptic drugs (AED) exposures during the first trimester of pregnancy in women with …