Systemic fungal infections pose a serious clinical problem. Treatment options are limited,
and antifungal drug resistance is increasing. In addition, a substantial proportion of patients …

Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial
community colonizing the mammalian gastrointestinal tract and has an important role in …

Current medical knowledge and research on patients' management are still evolving, and
several protocols on minimizing risk of infection by Candida spp. among the population have …

Candida albicans is a frequent colonizer of human mucosal surfaces as well as an
opportunistic pathogen. C. albicans is remarkably versatile in its ability to colonize diverse …

Fungal species have dynamic genomes and often exhibit genomic plasticity in response to
stress. This genome plasticity often comes with phenotypic consequences that affect fitness …

Previously, we identified long repeat sequences that are frequently associated with genome
rearrangements, including copy number variation (CNV), in many diverse isolates of the …

Understanding how microbial pathogens adapt to treatments, humans and clinical
environments is key to infer mechanisms of virulence, transmission and drug resistance …

Cross-species gene transfer is often associated with bacteria, which have evolved several
mechanisms that facilitate horizontal DNA exchange. However, the increased availability of …

Candida albicans is a diploid human fungal pathogen that displays significant genomic and
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …