Diagnosis and management of chronic pancreatitis: a review

VK Singh, D Yadav, PK Garg - Jama, 2019 - jamanetwork.com
Importance Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the
pancreas with a prevalence of 42 to 73 per 100 000 adults in the United States …

Genetic risk factors for pancreatic disorders

DC Whitcomb - Gastroenterology, 2013 - Elsevier
A combination of genetic, environmental, and metabolic factors contribute to the
development and recurrence of acute and chronic pancreatitis; information on all of these is …

Risk factors associated with pediatric acute recurrent and chronic pancreatitis: lessons from INSPPIRE

S Kumar, CY Ooi, S Werlin, M Abu-El-Haija… - JAMA …, 2016 - jamanetwork.com
Importance Pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) are
poorly understood. Objective To characterize and identify risk factors associated with ARP …

Recommendations for the classification of diseases as CFTR-related disorders

C Bombieri, M Claustres, K De Boeck, N Derichs… - Journal of Cystic …, 2011 - Elsevier
Several diseases have been clinically or genetically related to cystic fibrosis (CF), but a
consensus definition is lacking. Here, we present a proposal for consensus guidelines on …

Chronic pancreatitis: challenges and advances in pathogenesis, genetics, diagnosis, and therapy

H Witt, MV Apte, V Keim, JS Wilson - Gastroenterology, 2007 - Elsevier
Chronic pancreatitis (CP) is characterized by progressive pancreatic damage that eventually
results in significant impairment of exocrine as well as endocrine functions of the gland. In …

The Phenotypic Consequences of CFTR Mutations

RK Rowntree, A Harris - Annals of human genetics, 2003 - Wiley Online Library
Cystic fibrosis is a common autosomal recessive disorder that primarily affects the epithelial
cells in the intestine, respiratory system, pancreas, gall bladder and sweat glands. Over one …

English language version of the S3-consensus guidelines on chronic pancreatitis: Definition, aetiology, diagnostic examinations, medical, endoscopic and surgical …

A Hoffmeister, J Mayerle, C Beglinger… - Zeitschrift für …, 2015 - thieme-connect.com
Chronic pancreatitis is a disease of the pancreas in which recurrent inflammatory episodes
result in replacement of pancreatic parenchyma by fibrous connective tissue. This fibrotic …

S3-leitlinie pankreatitis–leitlinie der deutschen gesellschaft für gastroenterologie, verdauungs-und stoffwechselkrankheiten (DGVS)–september 2021–AWMF …

G Beyer, A Hoffmeister, P Michl… - Zeitschrift für …, 2022 - thieme-connect.com
Diese Leitlinie umfasst erstmals die akute wie auch die chronische Pankreatitis, um so
Übergänge der beiden ehemals getrennt wahrgenommenen Krankheitsbilder gemäß einem …

Multicenter approach to recurrent acute and chronic pancreatitis in the United States: the North American Pancreatitis Study 2 (NAPS2)

DC Whitcomb, D Yadav, S Adam, RH Hawes… - Pancreatology, 2008 - Elsevier
Background: Recurrent acute pancreatitis (RAP) and chronic pancreatitis (CP) are complex
syndromes associated with numerous etiologies, clinical variables and complications. We …

Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis

J LaRusch, J Jung, IJ General, MD Lewis… - PLoS …, 2014 - journals.plos.org
CFTR is a dynamically regulated anion channel. Intracellular WNK1-SPAK activation causes
CFTR to change permeability and conductance characteristics from a chloride-preferring to …