Alzheimer's disease: an update and insights into pathophysiology

MB Abubakar, KO Sanusi, A Ugusman… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is an irreversible brain disorder associated with slow, progressive
loss of brain functions mostly in older people. The disease processes start years before the …

[HTML][HTML] MicroRNAs in Alzheimer's disease: Potential diagnostic markers and therapeutic targets

S Liu, M Fan, Q Zheng, S Hao, L Yang, Q **a… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease, with cognitive
decline as the primary clinical feature. According to epidemiological statistics, 50 million …

Unraveling the role of miRNAs in the diagnosis, progression, and therapeutic intervention of Alzheimer's disease

NM Abdelmaksoud, AAM Sallam, AI Abulsoud… - … -Research and Practice, 2024 - Elsevier
Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …

Lipopolysaccharides (LPSs) as potent neurotoxic glycolipids in Alzheimer's disease (AD)

Y Zhao, VR Jaber, AI Pogue, NM Sharfman… - International Journal of …, 2022 - mdpi.com
Lipopolysaccharides (LPSs) are microbiome-derived glycolipids that are among the most
potent pro-inflammatory neurotoxins known. In Homo sapiens, the major sources of LPSs …

Insights into role of microRNA in Alzheimer's disease: from contemporary research to bedside perspective

M Bandakinda, A Mishra - International Journal of Biological …, 2023 - Elsevier
One of the most prevalent neurodegenerative disorders is Alzheimer's disease (AD). Despite
the pervasiveness of AD being considerable, the rates of both diagnosis and therapy are …

MicroRNAs as potential orchestrators of Alzheimer's disease-related pathologies: insights on current status and future possibilities

NZ Abuelezz, FE Nasr, MA AbdulKader… - Frontiers in Aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive and deleterious neurodegenerative disease,
strongly affecting the cognitive functions and memory of seniors worldwide. Around 58% of …

miR-143-3p inhibits aberrant tau phosphorylation and amyloidogenic processing of APP by directly targeting DAPK1 in Alzheimer's disease

L Wang, X Shui, Y Mei, Y **a, G Lan, L Hu… - International Journal of …, 2022 - mdpi.com
The neuropathology of Alzheimer's disease (AD) is characterized by intracellular
aggregation of hyperphosphorylated tau and extracellular accumulation of beta-amyloid …

Cerebrospinal fluid microRNAs as potential biomarkers in Alzheimer's disease

A Noor Eddin, K Hamsho, G Adi… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the leading form of dementia worldwide, but its early detection
and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous …

The role of microRNAs in neurobiology and pathophysiology of the hippocampus

SK Rashidi, A Kalirad, S Rafie, E Behzad… - Frontiers in molecular …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are short non-coding and well-conserved RNAs that are linked to
many aspects of development and disorders. MicroRNAs control the expression of genes …

Death Induced by Survival gene Elimination (DISE) correlates with neurotoxicity in Alzheimer's disease and aging

B Paudel, SY Jeong, CP Martinez, A Rickman… - Nature …, 2024 - nature.com
Alzheimer's disease (AD) is characterized by progressive neurodegeneration, but the
specific events that cause cell death remain poorly understood. Death Induced by Survival …