Due to the intrinsic non-invasive nature, cost-effectiveness, high safety, and real-time
capabilities, besides diagnostic imaging, ultrasound as a typical mechanical wave has been …

Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …

Neural circuitry is typically modulated via invasive brain implants and tethered optical fibres
in restrained animals. Here we show that wide-field illumination in the second near-infrared …

The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

Ultrasonic neuromodulation has the unique potential to provide non-invasive control of
neural activity in deep brain regions with high spatial precision and without chemical or …

Transcranial focused ultrasound (tFUS) is a promising neuromodulation technique, but its
mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct …

Acoustic microfluidic devices are powerful tools that use sound waves to manipulate micro-
or nanoscale objects or fluids in analytical chemistry and biomedicine. Their simple device …

Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …

In the mammalian nervous system, billions of neurons connected by quadrillions of
synapses exchange electrical, chemical and mechanical signals. Disruptions to this network …

Bidirectional interfacing with the nervous system enables neuroscience research, diagnosis,
and therapy. This two-way communication allows us to monitor the state of the brain and its …