“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates

SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …

The fluorous effect in biomolecular applications

M Cametti, B Crousse, P Metrangolo, R Milani… - Chemical Society …, 2012 - pubs.rsc.org
From being a niche area only a few decades ago, fluorous chemistry has gained momentum
and is, nowadays, a fervent area of research. It has brought forth, in fact, numerous …

Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

TJ Boltje, T Buskas, GJ Boons - Nature chemistry, 2009 - nature.com
Synthetic oligosaccharides and glycoconjugates are increasingly used as probes for
biological research and as lead compounds for drug and vaccine discovery. These …

Glycan microarrays for decoding the glycome

CD Rillahan, JC Paulson - Annual review of biochemistry, 2011 - annualreviews.org
In the last decade, glycan microarrays have revolutionized the analysis of the specificity of
glycan-binding proteins (GBPs), providing information that simultaneously illuminates the …

Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to …

V Percec, P Leowanawat, HJ Sun… - Journal of the …, 2013 - ACS Publications
The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …

Chemical strategies for generating protein biochips

P Jonkheijm, D Weinrich, H Schröder… - Angewandte Chemie …, 2008 - Wiley Online Library
Protein biochips are at the heart of many medical and bioanalytical applications. Increasing
interest has been focused on surface activation and subsequent functionalization strategies …

Carbohydrate microarrays

S Park, JC Gildersleeve, O Blixt, I Shin - Chemical Society Reviews, 2013 - pubs.rsc.org
In the last decade, carbohydrate microarrays have been core technologies for analyzing
carbohydrate-mediated recognition events in a high-throughput fashion. A number of …

Toward automated oligosaccharide synthesis

CH Hsu, SC Hung, CY Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …

Sweet spots in functional glycomics

JC Paulson, O Blixt, BE Collins - Nature chemical biology, 2006 - nature.com
Abstract Information contained in the mammalian glycome is decoded by glycan-binding
proteins (GBPs) that mediate diverse functions including host-pathogen interactions, cell …

Glycan microarrays from construction to applications

Y Kim, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Through their specific interactions with proteins, cellular glycans play key roles in a wide
range of physiological and pathological processes. One of the main goals of research in the …