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“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates
SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …
significant roles in a variety of vital biological processes. Access to unique and …
The fluorous effect in biomolecular applications
From being a niche area only a few decades ago, fluorous chemistry has gained momentum
and is, nowadays, a fervent area of research. It has brought forth, in fact, numerous …
and is, nowadays, a fervent area of research. It has brought forth, in fact, numerous …
Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research
TJ Boltje, T Buskas, GJ Boons - Nature chemistry, 2009 - nature.com
Synthetic oligosaccharides and glycoconjugates are increasingly used as probes for
biological research and as lead compounds for drug and vaccine discovery. These …
biological research and as lead compounds for drug and vaccine discovery. These …
Glycan microarrays for decoding the glycome
In the last decade, glycan microarrays have revolutionized the analysis of the specificity of
glycan-binding proteins (GBPs), providing information that simultaneously illuminates the …
glycan-binding proteins (GBPs), providing information that simultaneously illuminates the …
Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to …
The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …
dendrimers with the monosaccharides d-mannose and d-galactose and the disaccharide d …
Chemical strategies for generating protein biochips
P Jonkheijm, D Weinrich, H Schröder… - Angewandte Chemie …, 2008 - Wiley Online Library
Protein biochips are at the heart of many medical and bioanalytical applications. Increasing
interest has been focused on surface activation and subsequent functionalization strategies …
interest has been focused on surface activation and subsequent functionalization strategies …
Carbohydrate microarrays
S Park, JC Gildersleeve, O Blixt, I Shin - Chemical Society Reviews, 2013 - pubs.rsc.org
In the last decade, carbohydrate microarrays have been core technologies for analyzing
carbohydrate-mediated recognition events in a high-throughput fashion. A number of …
carbohydrate-mediated recognition events in a high-throughput fashion. A number of …
Toward automated oligosaccharide synthesis
CH Hsu, SC Hung, CY Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
Carbohydrates have been shown to play important roles in biological processes. The pace
of development in carbohydrate research is, however, relatively slow due to the problems …
of development in carbohydrate research is, however, relatively slow due to the problems …
Sweet spots in functional glycomics
JC Paulson, O Blixt, BE Collins - Nature chemical biology, 2006 - nature.com
Abstract Information contained in the mammalian glycome is decoded by glycan-binding
proteins (GBPs) that mediate diverse functions including host-pathogen interactions, cell …
proteins (GBPs) that mediate diverse functions including host-pathogen interactions, cell …
Glycan microarrays from construction to applications
Y Kim, JY Hyun, I Shin - Chemical Society Reviews, 2022 - pubs.rsc.org
Through their specific interactions with proteins, cellular glycans play key roles in a wide
range of physiological and pathological processes. One of the main goals of research in the …
range of physiological and pathological processes. One of the main goals of research in the …