The multiple roles of interferon regulatory factor family in health and disease

L Wang, Y Zhu, N Zhang, Y **an, Y Tang, J Ye… - … and Targeted Therapy, 2024 - nature.com
Abstract Interferon Regulatory Factors (IRFs), a family of transcription factors, profoundly
influence the immune system, impacting both physiological and pathological processes …

The SAGA acetyltransferase module is required for the maintenance of MAF and MYC oncogenic gene expression programs in multiple myeloma

YJC Chen, GB Bhaskara, Y Lu, K Lin… - Genes & …, 2024 - genesdev.cshlp.org
Despite recent advances in therapeutic treatments, multiple myeloma (MM) remains an
incurable malignancy. Epigenetic factors contribute to the initiation, progression, relapse …

Structure based computational RNA design towards MafA transcriptional repressor implicated in multiple myeloma

GY Akdeniz, AC Timuçin - Journal of Molecular Graphics and Modelling, 2024 - Elsevier
Multiple myeloma is recognized as the second most common hematological cancer. MafA
transcriptional repressor is an established mediator of myelomagenesis. While there are …