AuNPs as an important inorganic nanoparticle applied in drug carrier systems

W Li, Z Cao, R Liu, L Liu, H Li, X Li, Y Chen… - Artificial cells …, 2019 - Taylor & Francis
Gold nanoparticles (AuNPs), as a kind of inorganic nanoparticle, have been gradually
recognized as one of the most promising nanomaterials, which is attributed to their unique …

Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies

E Bongaerts, TS Nawrot, T Van Pee, M Ameloot… - Particle and Fibre …, 2020 - Springer
Fetal development is a crucial window of susceptibility in which exposure may lead to
detrimental health outcomes at birth and later in life. The placenta serves as a gatekeeper …

Penetration and translocation of functional inorganic nanomaterials into biological barriers

Y Cong, D Baimanov, Y Zhou, C Chen… - Advanced Drug Delivery …, 2022 - Elsevier
With excellent physicochemical properties, inorganic nanomaterials (INMs) have exhibited a
series of attractive applications in biomedical fields. Biological barriers prevent successful …

Recent insights on indirect mechanisms in developmental toxicity of nanomaterials

BB Dugershaw, L Aengenheister, SSK Hansen… - Particle and Fibre …, 2020 - Springer
Background Epidemiological and animal studies provide compelling indications that
environmental and engineered nanomaterials (NMs) pose a risk for pregnancy, fetal …

[HTML][HTML] Transcriptomic profiling reveals differential cellular response to copper oxide nanoparticles and polystyrene nanoplastics in perfused human placenta

S Chortarea, G Gupta, LA Saarimäki… - Environment …, 2023 - Elsevier
The growing nanoparticulate pollution (eg engineered nanoparticles (NPs) or nanoplastics)
has been shown to pose potential threats to human health. In particular, sensitive …

Nanoparticles in pregnancy: the next frontier in reproductive therapeutics

N Pritchard, T Kaitu'u-Lino, L Harris… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Nanotechnology involves the engineering of structures on a molecular
level. Nanomedicine and nano-delivery systems have been designed to deliver therapeutic …

Plasma proteins facilitates placental transfer of polystyrene particles

MM Gruber, B Hirschmugl, N Berger, M Holter… - Journal of …, 2020 - Springer
Background Nanoparticles, which are exposed to biological fluids are rapidly interacting
with proteins and other biomolecules forming a corona. In addition to dimension, charge and …

Delivery technologies for women's health applications

KL Swingle, AS Ricciardi, WH Peranteau… - Nature Reviews …, 2023 - nature.com
The treatment of women's health-related conditions, including reproductive tract and
pregnancy disorders, faces distinct challenges and microenvironments, such as the vaginal …

[HTML][HTML] Experimental human placental models for studying uptake, transport and toxicity of micro-and nanoplastics

HM Dusza, J van Boxel, MBM van Duursen… - Science of The Total …, 2023 - Elsevier
Micro-and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs …

Creating mini-pregnancy models in vitro with clinical perspectives

JY Park, H Lim, J Qin, LP Lee - EBioMedicine, 2023 - thelancet.com
During the last decade, organs-on-chips or organoids microphysiological analysis platforms
(MAP) have garnered attention in the practical applications of disease models, drug …