Forkhead box transcription factor, FOXM1 is implicated in several cellular processes such as
proliferation, cell cycle progression, cell differentiation, DNA damage repair, tissue …

Despite the recent introduction of new effective systemic agents, the survival of patients with
hepatocellular carcinoma (HCC) at advanced stages remains dismal. This underscores the …

Some types of circular RNA (circRNA) are aberrantly expressed in human diseases
including hepatocellular carcinoma (HCC). However, its regulation mechanism and …

Hepatocellular carcinoma is one of the most common malignant tumors. M6A is a novel
epigenetic modification that have been emerged as vital regulators for the progression of …

Background and Aims Activated hepatocytes are hypothesized to be a major source of
signals that drive cirrhosis, but the biochemical pathways that convert hepatocytes into such …

Liver cancer, hepatocellular carcinoma (HCC) in particular, is one of the deadliest cancers
worldwide. Although the etiologies for liver oncogenesis are relatively well defined, the exact …

The Hippo pathway is a central regulator of organ size and tissue homeostasis. Hippo
kinases and adaptor proteins mediate the phosphorylation and inactivation of YAP and TAZ …

Abstract Background Forkhead box M1 (FOXM1) is a proliferation-associated transcription
factor of the forkhead box proteins superfamily, which includes four isoforms FOXM1a, b, c …

Verteporfin (VP) has long been clinically used to treat age-related macular degeneration
(AMD) through photodynamic therapy (PDT). Recent studies have reported a significant anti …

H19 is an imprinted long noncoding RNA abundantly expressed in embryonic liver and
repressed after birth. We show that H19 serves as a lipid sensor by synergizing with the …