Three-dimensional in vitro tumor spheroid models for evaluation of anticancer therapy: recent updates
Simple Summary Cancer is a global public health issue. The development and use of in vitro
cellular models with pre-clinical animal models are essential to elucidate the complex …
cellular models with pre-clinical animal models are essential to elucidate the complex …
Revolutionizing the female reproductive system research using microfluidic chip platform
J Yan, T Wu, J Zhang, Y Gao, JM Wu… - Journal of …, 2023 - Springer
Comprehensively understanding the female reproductive system is crucial for safeguarding
fertility and preventing diseases concerning women's health. With the capacity to simulate …
fertility and preventing diseases concerning women's health. With the capacity to simulate …
Cancer Organoids as reliable disease models to drive clinical development of novel therapies
G Blandino, R Satchi-Fainaro, I Tinhofer… - Journal of Experimental …, 2024 - Springer
Abstract On September 23–24 (2024) the 6th Workshop IRE on Translational Oncology,
titled “Cancer Organoids as Reliable Disease Models to Drive Clinical Development of …
titled “Cancer Organoids as Reliable Disease Models to Drive Clinical Development of …
Multicompartmentalized microvascularized tumor-on-a-chip to study tumor-stroma interactions and drug resistance in ovarian cancer
S Plesselova, K Calar, H Axemaker, E Sahly… - Cellular and Molecular …, 2024 - Springer
Introduction The majority of ovarian cancer (OC) patients receiving standard of care
chemotherapy develop chemoresistance within 5 years. The tumor microenvironment (TME) …
chemotherapy develop chemoresistance within 5 years. The tumor microenvironment (TME) …
Paracrine Ovarian Cancer Cell‐Derived CSF1 Signaling Regulates Macrophage Migration Dynamics in a 3D Microfluidic Model that Recapitulates in vivo Infiltration …
AL Scott, DE Jazwinska, DG Kulawiec… - Advanced …, 2024 - Wiley Online Library
A high density of macrophages in the ovarian cancer microenvironment is associated with
disease progression and poor outcomes. Understanding cancer‐macrophage interaction …
disease progression and poor outcomes. Understanding cancer‐macrophage interaction …
Vascularized tumor models for the evaluation of drug delivery systems: a paradigm shift
As the conversion rate of preclinical studies for cancer treatment is low, user-friendly models
that mimic the pathological microenvironment and drug intake with high throughput are …
that mimic the pathological microenvironment and drug intake with high throughput are …
MicroRNAs Can Influence Ovarian Cancer Progression by Dysregulating Integrin Activity
Z Fasoulakis, MZ Psarommati, A Papapanagiotou… - Cancers, 2023 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression, with significant implications in ovarian cancer development and progression …
expression, with significant implications in ovarian cancer development and progression …
Comparative study on the mutation spectrum of L‐MYC and C‐MYC genes of blood cfDNA in patients with ovarian cancer and healthy females
S Shabir, A Asiaf - Journal of Obstetrics and Gynaecology …, 2023 - Wiley Online Library
Background This study aimed at detecting the mutations of L‐MYC and C‐MYC genes in
ovarian cancer (OC) patients and healthy female volunteers using cell‐free DNA (cfDNA) …
ovarian cancer (OC) patients and healthy female volunteers using cell‐free DNA (cfDNA) …
A Novel Silicon Titanium-Diboride Substrate Supports Growth, Aggregation, Mechanosensing, and Invasiveness of Ovarian Cancer Cells to Assess Therapeutic …
M Quttina, D McPhail, M Eisenbrandt… - … , and Invasiveness of … - papers.ssrn.com
Cancer cells adhere to biological boundaries such as the extracellular matrix (ECM) and
basement membranes, a process that underpins metastatic niche and distinct cellular …
basement membranes, a process that underpins metastatic niche and distinct cellular …