Inflammation is one of the major causative factor of cancer and chronic inflammation is
involved in all the major steps of cancer initiation, progression metastasis and drug …

Polyphenols are naturally occurring compounds found in abundance in fruits and
vegetables. Their health-promoting properties and their use in the prevention and treatment …

DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …

DNA replication is a highly demanding process regarding the energy and material supply
and must be precisely regulated, involving multiple cellular feedbacks. The slowing down or …

Background Metabolic reprogramming contributes significantly to tumor development and is
tightly linked to drug resistance. The chemotherapeutic agent etoposide (VP-16) has been …

Hepatocellular carcinoma (HCC), as a common malignancy of the liver, is the second
leading cause of cancer-related death in the world and mostly occurs in patients with a …

Kaempferol is a well-known antioxidant found in many plants and plant-based foods. In
plants, kaempferol is present mainly in the form of glycoside derivatives. In this work, we …

Leukemia comprises a group of hematological malignancies responsible for 8% of all
cancers and is the most common cancer in children. Despite significant improvements in …

Context Curcumin, a polyphenolic compound extracted from the rhizome of the tropical plant
Curcuma longa L.(Zingiberaceae), has been considered as a cancer chemopreventive drug …

Curcuma longa has been mentioned in the Indian system of medicine for the management
of a wide range of diseases. C. longa and its metabolites like curcumin, ar-turmerone …