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The Warburg effect on radioresistance: Survival beyond growth
The Warburg effect is a phenomenon in which cancer cells rely primarily on glycolysis rather
than oxidative phosphorylation, even in the presence of oxygen. Although evidence of its …
than oxidative phosphorylation, even in the presence of oxygen. Although evidence of its …
Cytokines secreted by inflamed oral mucosa: implications for oral cancer progression
The oral mucosa has an essential role in protecting against physical, microbial, and
chemical harm. Compromise of this barrier triggers a wound healing response. Key events …
chemical harm. Compromise of this barrier triggers a wound healing response. Key events …
DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in …
Thyroid receptor‐interacting protein 13 (TRIP13), a protein of the AAA‐ATPase family, is
upregulated in various human cancers, including colorectal cancer (CRC). This study …
upregulated in various human cancers, including colorectal cancer (CRC). This study …
TRIP13 regulates progression of gastric cancer through stabilising the expression of DDX21
G Zhang, R Yang, B Wang, Q Yan, P Zhao… - Cell Death & …, 2024 - nature.com
GC (Gastric cancer) is one of the most common malignant tumours, with over 95% of gastric
cancer patients being adenocarcinoma and most gastric cancer patients having no apparent …
cancer patients being adenocarcinoma and most gastric cancer patients having no apparent …
[HTML][HTML] Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma
Thyroid hormone receptor-interacting protein 13 (TRIP13) is involved in cancer progression,
but its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. Thus, we assessed the …
but its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. Thus, we assessed the …
TRIP13 overexpression promotes gefitinib resistance in non‑small cell lung cancer via regulating autophagy and phosphorylation of the EGFR signaling pathway
Z **ao, M Li, X Zhang, X Rong… - Oncology Reports, 2023 - spandidos-publications.com
Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancers and remains
the most common cause of cancer-related death. Epidermal growth factor receptor (EGFR) …
the most common cause of cancer-related death. Epidermal growth factor receptor (EGFR) …
Decoding the research landscape of drug resistance and therapeutic approaches in head and neck cancer: a bibliometric analysis from 2000 to 2023
Q Han, J Shi, J Liu, Y Fu, Z Li, H Guo, X Guan… - Frontiers in …, 2024 - frontiersin.org
Introduction: Head and neck cancer is one of the most common tumors worldwide. However,
drug resistance in its treatment has become a major factor limiting the efficacy. This study …
drug resistance in its treatment has become a major factor limiting the efficacy. This study …
A plant nonenveloped double-stranded RNA virus activates and co-opts BNIP3-mediated mitophagy to promote persistent infection in its insect vector
Q Liang, J Wan, H Liu, D Jia, Q Chen, A Wang, T Wei - Autophagy, 2023 - Taylor & Francis
Mitophagy that selectively eliminates damaged mitochondria is an essential mitochondrial
quality control mechanism. Recently, mitophagy has been shown to be induced in host cells …
quality control mechanism. Recently, mitophagy has been shown to be induced in host cells …
FAM64A promotes HNSCC tumorigenesis by mediating transcriptional autoregulation of FOXM1
X Zhao, H Chen, Y Qiu, L Cui - International Journal of Oral Science, 2022 - nature.com
Head and neck squamous cell carcinoma (HNSCC) still lacks effective targeted treatment.
Therefore, exploring novel and robust molecular targets is critical for improving the clinical …
Therefore, exploring novel and robust molecular targets is critical for improving the clinical …
TRIP13 plays an important role in the sensitivity of leukemia cell response to sulforaphane therapy
L Liu, B Liao, R Fan, Y Liu, A Li, L Liu, Y Li, J Li - ACS omega, 2024 - ACS Publications
Sulforaphane is one of the most characterized isothiocyanate compounds in cruciferous
vegetables and shows anticancer effects, especially antileukemia properties. However, the …
vegetables and shows anticancer effects, especially antileukemia properties. However, the …