Valvular heart disease and calcification in CKD: more common than appreciated
Ischaemic heart disease, sudden cardiac death and arrhythmias, heart failure, stroke and
peripheral arterial disease make up> 50% of the causes of death in advanced chronic …
peripheral arterial disease make up> 50% of the causes of death in advanced chronic …
Role of oxidative stress in calcific aortic valve disease and its therapeutic implications
HZE Greenberg, G Zhao, AM Shah… - Cardiovascular …, 2022 - academic.oup.com
Calcific aortic valve disease (CAVD) is the end result of active cellular processes that lead to
the progressive fibrosis and calcification of aortic valve leaflets. In western populations …
the progressive fibrosis and calcification of aortic valve leaflets. In western populations …
Evolution and prognostic impact of cardiac damage after aortic valve replacement
Background The impact of aortic valve replacement (AVR) on progression/regression of
extravalvular cardiac damage and its association with subsequent prognosis is unknown …
extravalvular cardiac damage and its association with subsequent prognosis is unknown …
Spatiotemporal multi-omics map** generates a molecular atlas of the aortic valve and reveals networks driving disease
Background: No pharmacological therapy exists for calcific aortic valve disease (CAVD),
which confers a dismal prognosis without invasive valve replacement. The search for …
which confers a dismal prognosis without invasive valve replacement. The search for …
Slower progress of aortic valve calcification with vitamin K supplementation: results from a prospective interventional proof-of-concept study
VM Brandenburg, S Reinartz, N Kaesler, T Krüger… - Circulation, 2017 - Am Heart Assoc
Slower Progress of Aortic Valve Calcification With Vitamin K Supplementation | Circulation
Science Volunteer Warning signs SearchSearch Advanced Search Donate Circulation logo Hello …
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Secreted factors from proinflammatory macrophages promote an osteoblast-like phenotype in valvular interstitial cells
Objective: Resident valvular interstitial cells (VICs) activate to myofibroblasts during aortic
valve stenosis progression, which further promotes fibrosis or even differentiate into …
valve stenosis progression, which further promotes fibrosis or even differentiate into …
Development of calcific aortic valve disease: do we know enough for new clinical trials?
Calcific aortic valve disease (CAVD), previously thought to represent a passive
degeneration of the valvular extracellular matrix (VECM), is now regarded as an intricate …
degeneration of the valvular extracellular matrix (VECM), is now regarded as an intricate …
Treatment and prevention of lipoprotein (a)-mediated cardiovascular disease: the emerging potential of RNA interference therapeutics
DI Swerdlow, DA Rider, A Yavari… - Cardiovascular …, 2022 - academic.oup.com
Lipid-and lipoprotein-modifying therapies have expanded substantially in the last 25 years,
resulting in reduction in the incidence of major adverse cardiovascular events. However, no …
resulting in reduction in the incidence of major adverse cardiovascular events. However, no …
[HTML][HTML] Burden of valvular heart disease, 1990-2017: results from the Global Burden of Disease Study 2017
J Chen, W Li, M **ang - Journal of global health, 2020 - ncbi.nlm.nih.gov
Background Valvular heart disease (VHD) is expected to cause an increase in public-health
problems in the coming years, especially in elderly populations. We aim to estimate the …
problems in the coming years, especially in elderly populations. We aim to estimate the …
[HTML][HTML] Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization
Abstract Introduction Hydrogen sulfide (H 2 S) was revealed to inhibit aortic valve
calcification and inflammation was implicated in the pathogenesis of calcific aortic valve …
calcification and inflammation was implicated in the pathogenesis of calcific aortic valve …