Adipokines: new potential therapeutic target for obesity and metabolic, rheumatic, and cardiovascular diseases

L Recinella, G Orlando, C Ferrante… - Frontiers in …, 2020 - frontiersin.org
Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Adipose tissue-derived signatures for obesity and type 2 diabetes: adipokines, batokines and microRNAs

MW Lee, M Lee, KJ Oh - Journal of clinical medicine, 2019 - mdpi.com
Obesity is one of the main risk factors for type 2 diabetes mellitus (T2DM). It is closely related
to metabolic disturbances in the adipose tissue that primarily functions as a fat reservoir. For …

The anti-inflammatory effects of aerobic exercise training in patients with type 2 diabetes: A systematic review and meta-analysis

G Papagianni, C Panayiotou, M Vardas, N Balaskas… - Cytokine, 2023 - Elsevier
Background Type 2 diabetes mellitus (T2DM) is a low-grade, chronic inflammatory disease,
associated with increased cardiovascular risk. The purpose of this systematic review/meta …

Vaspin in obesity and diabetes: pathophysiological and clinical significance

M Blüher - Endocrine, 2012 - Springer
Vaspin (visceral adipose tissue-derived serpin; serpinA12) was originally identified as an
adipokine, which is predominantly secreted from visceral adipose tissue in Otsuka Long …

Role of omentin, vaspin, cardiotrophin-1, TWEAK and NOV/CCN3 in obesity and diabetes development

X Escoté, S Gómez-Zorita, M López-Yoldi… - International journal of …, 2017 - mdpi.com
Adipose tissue releases bioactive mediators called adipokines. This review focuses on the
effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of …

Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation

G Flehmig, M Scholz, N Klöting, M Fasshauer… - PloS one, 2014 - journals.plos.org
In obesity, elevated fat mass and ectopic fat accumulation are associated with changes in
adipokine secretion, which may link obesity to inflammation and the development of insulin …

The differential anti‐inflammatory effects of exercise modalities and their association with early carotid atherosclerosis progression in patients with type 2 diabetes

NPE Kadoglou, G Fotiadis, A Kapelouzou… - Diabetic …, 2013 - Wiley Online Library
Objective Adipokines, visfatin, apelin, vaspin and ghrelin have emerged as novel
cardiovascular risk factors. We aimed to evaluate the effects of different exercise modalities …

[HTML][HTML] Role of obesity-associated dysfunctional adipose tissue in cancer: a molecular nutrition approach

PL Prieto-Hontoria, P Pérez-Matute… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary,
lifestyle and environmental factors, which favors a chronic positive energy balance, leading …

The role of vaspin in the development of metabolic and glucose tolerance disorders and atherosclerosis

R Dimova, T Tankova - BioMed research international, 2015 - Wiley Online Library
In recent years, most research efforts have been focused on studying insulin‐sensitizing
adipokines. One of the most recently discovered adipokines is vaspin, a visceral adipose …

Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat …

S Phalitakul, M Okada, Y Hara, H Yamawaki - Pharmacological Research, 2011 - Elsevier
Vaspin (visceral adipose tissue-derived serine protease inhibitor) was recently identified as
a novel adipocytokine with insulin-sensitizing effects. We hypothesized that vaspin could …