Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …

Disruptions of circadian rhythms and sleep cycles are common among neurodegenerative
diseases and can occur at multiple levels. Accumulating evidence reveals a bidirectional …

Background Cognitive impairment, a defining feature of dementia, plays an important role in
the compromised functional independence that characterises the condition. Cognitive …

Combined cognitive and physical exercise interventions have potential to elicit cognitive
benefits in older adults with mild cognitive impairment (MCI) or dementia. This meta-analysis …

Aims To assess the potential multi-domain benefits of exercise interventions on patients with
Alzheimer's disease (AD), as well as to determine the specific effects of different exercise …

Objective: The purpose of this meta-analysis was to examine the effects of physical activity
(PA) on cognition and activities of daily living in adults with Alzheimer's Disease (AD) …

The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian
rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms …

Background Exercise is often proposed as a non-pharmacological intervention to delay
cognitive decline in people with dementia, but evidence remains inconclusive. Previous …

Background: Cognitive therapy is a well-established intervention for treating elderly suffering
from dementia. In particular, reality orientation and skills training seem to be effective …

Alzheimer's disease (AD) is a very disabling disease. Pathologically, it is characterized by
the presence of amyloid plaques and neurofibrillary tangles in the brain that results in …