An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

[HTML][HTML] The SARS-CoV-2 mutations versus vaccine effectiveness: New opportunities to new challenges

JA Malik, S Ahmed, A Mir, M Shinde, O Bender… - Journal of infection and …, 2022 - Elsevier
Abstract Background The SARS-CoV-2 coronavirus epidemic is hastening the discovery of
the most efficient vaccines. The development of cost-effective vaccines seems to be the only …

Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic

SSA Karim, QA Karim - The lancet, 2021 - thelancet.com
SARS-CoV-2 variant of concern (VoC), omicron, 2 was reported. Omicron emerged in a
COVID-19-weary world in which anger and frustration with the pandemic are rife amid …

Detection of a SARS-CoV-2 variant of concern in South Africa

H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh… - Nature, 2021 - nature.com
Continued uncontrolled transmission of SARS-CoV-2 in many parts of the world is creating
conditions for substantial evolutionary changes to the virus,. Here we describe a newly …

Comparison of patients infected with Delta versus Omicron COVID-19 variants presenting to Paris emergency departments: a retrospective cohort study

D Bouzid, B Visseaux, C Kassasseya… - Annals of internal …, 2022 - acpjournals.org
Background: At the end of 2021, the B. 1.1. 529 SARS-CoV-2 variant (Omicron) wave
superseded the B. 1.617. 2 variant (Delta) wave. Objective: To compare baseline …

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

X Deng, MA Garcia-Knight, MM Khalid, V Servellita… - Cell, 2021 - cell.com
We identified an emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant by viral whole-genome sequencing of 2,172 nasal/nasopharyngeal swab samples …

A paper-based assay for the colorimetric detection of SARS-CoV-2 variants at single-nucleotide resolution

T Zhang, R Deng, Y Wang, C Wu, K Zhang… - Nature Biomedical …, 2022 - nature.com
The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
highlighted the need for versatile diagnostic assays that can discriminate among emerging …

SARS-CoV-2 vaccines based on the spike glycoprotein and implications of new viral variants

D Martínez-Flores, J Zepeda-Cervantes… - Frontiers in …, 2021 - frontiersin.org
Coronavirus 19 Disease (COVID-19) originating in the province of Wuhan, China in 2019, is
caused by the severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), whose …

[HTML][HTML] Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

X Deng, MA Garcia-Knight, MM Khalid, V Servellita… - MedRxiv, 2021 - ncbi.nlm.nih.gov
We identified a novel SARS-CoV-2 variant by viral whole-genome sequencing of 2,172
nasal/nasopharyngeal swab samples from 44 counties in California. Named B. 1.427/B …

SARS-COV-2 variants: differences and potential of immune evasion

SM Hirabara, TDA Serdan, R Gorjao… - Frontiers in cellular …, 2022 - frontiersin.org
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …