The use of peptides as therapeutics has often been associated with several drawbacks such
as poor absorption, low stability to proteolytic digestion, and fast clearance. Peptidomimetics …

The ability to selectively modify proteins at two or more defined locations opens new
avenues for manipulating, engineering, and studying living systems. As a chemical biology …

Although epoxy asphalt possesses excellent mechanical properties, good fatigue
resistance, and high durability, it is not recyclable. The aim of this study is to apply the …

Peptides act as biological mediators and play a key role of various physiological activities.
Sulfur-containing peptides are widely used in natural products and drug molecules due to …

Peptide heterodimers are prevalent in nature, which are not only functional macromolecules
but molecular tools for chemical and synthetic biology. Computational methods have also …

The use of synthetic bridges as surrogates for disulfide bonds has emerged as a practical
strategy to obviate the poor stability of some disulfide‐containing peptides. However …

The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic is an
unprecedented global health emergency causing more than 4.2 million fatalities as of 30 …

Fe (Pc)-Catalyzed aerobic oxidation of thiols for the synthesis of disulfides has been
developed under mild reaction conditions. In addition, an aerobic oxidative cross …

The ruthenium‐catalyzed azide‐alkyne cycloaddition (RuAAC) gives access to 1, 5‐
disubstitued triazoles in a single atom‐economical step and offers advantages compared to …

Abstracts Conotoxins, isolated from the venom of carnivorous marine snails of the Conus
genus, are disulfide-rich peptides and proteins with well-defined three-dimensional …