Functions of galanin, spexin and kisspeptin in metabolism, mood and behaviour

EG Mills, C Izzi-Engbeaya, A Abbara… - Nature Reviews …, 2021‏ - nature.com
The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

The role of polymorphism in various potential genes on polycystic ovary syndrome susceptibility and pathogenesis

H Chaudhary, J Patel, NK Jain, R Joshi - Journal of ovarian research, 2021‏ - Springer
Polycystic ovary syndrome (PCOS) is the most common endocrinopathies affecting the early
reproductive age in women, whose pathophysiology perplexes many researchers till today …

Functional hypothalamic amenorrhea: an endocrine society clinical practice guideline

CM Gordon, KE Ackerman, SL Berga… - The Journal of …, 2017‏ - academic.oup.com
Abstract Cosponsoring Associations: The American Society for Reproductive Medicine, the
European Society of Endocrinology, and the Pediatric Endocrine Society. This guideline was …

Molecular communication and nanonetwork for targeted drug delivery: A survey

UAK Chude-Okonkwo, R Malekian… - … Surveys & Tutorials, 2017‏ - ieeexplore.ieee.org
Molecular communication (MC) and molecular network (MN) are communication paradigms
that use biochemical signaling to achieve information exchange among naturally and …

Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders

A Abbara, PC Eng, M Phylactou… - The Journal of …, 2020‏ - Am Soc Clin Investig
BACKGROUND Kisspeptin is a key regulator of hypothalamic gonadotropin-releasing
hormone (GnRH) neurons and is essential for reproductive health. A specific kisspeptin …

[HTML][HTML] Physiology of GNRH and gonadotropin secretion

P Marques, K Skorupskaite, KS Rozario… - Endotext …, 2022‏ - ncbi.nlm.nih.gov
Gonadotropin hormone-releasing hormone (GnRH) is the key regulator of the reproductive
axis. Its pulsatile secretion determines the pattern of secretion of the gonadotropins follicle …

The emerging therapeutic potential of kisspeptin and neurokinin B

B Patel, K Koysombat, EG Mills, J Tsoutsouki… - Endocrine …, 2024‏ - academic.oup.com
Kisspeptin (KP) and neurokinin B (NKB) are neuropeptides that govern the reproductive
endocrine axis through regulating hypothalamic gonadotropin-releasing hormone (GnRH) …

Comprehensive review on kisspeptin and its role in reproductive disorders

H Clarke, WS Dhillo… - Endocrinology and …, 2015‏ - synapse.koreamed.org
Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …

Current understanding of hypothalamic amenorrhoea

RE Roberts, L Farahani, L Webber… - … in endocrinology and …, 2020‏ - journals.sagepub.com
Hypothalamic amenorrhoea (HA) accounts for approximately 30% of cases of secondary
amenorrhoea in women of reproductive age. It is caused by deficient secretion of …

The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans

C Izzi‐Engbeaya, AN Comninos… - Diabetes, Obesity …, 2018‏ - Wiley Online Library
Aims To investigate the effect of kisspeptin on glucose‐stimulated insulin secretion and
appetite in humans. Materials and methods In 15 healthy men (age: 25.2±1.1 years; BMI …