Molecular markers associated with development and progression of potentially premalignant oral epithelial lesions: Current knowledge and future implications
Identification and management of potentially premalignant oral epithelial lesions (PPOELs)
at highest risk of malignant transformation holds great promise for successful secondary …
at highest risk of malignant transformation holds great promise for successful secondary …
Targeting FOXM1 in cancer
M Halasi, AL Gartel - Biochemical pharmacology, 2013 - Elsevier
Oncogenic transcription factor FOXM1 is overexpressed in the majority of human cancers. In
addition, FOXM1 has been implicated in cell migration, invasion, angiogenesis and …
addition, FOXM1 has been implicated in cell migration, invasion, angiogenesis and …
Identification of cell cycle–regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
GD Grant, L Brooks 3rd, X Zhang… - Molecular biology of …, 2013 - Am Soc Cell Biol
We identify the cell cycle–regulated mRNA transcripts genome-wide in the osteosarcoma-
derived U2OS cell line. This results in 2140 transcripts map** to 1871 unique cell cycle …
derived U2OS cell line. This results in 2140 transcripts map** to 1871 unique cell cycle …
The transcription factor FOXM1 (Forkhead box M1): proliferation-specific expression, transcription factor function, target genes, mouse models, and normal biological …
I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor,
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …
which stimulates cell proliferation and exhibits a proliferation-specific expression pattern …
FOXM1 (Forkhead box M1) in tumorigenesis: overexpression in human cancer, implication in tumorigenesis, oncogenic functions, tumor-suppressive properties, and …
I Wierstra - Advances in cancer research, 2013 - Elsevier
Abstract FOXM1 (Forkhead box M1) is a typical proliferation-associated transcription factor
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …
and is also intimately involved in tumorigenesis. FOXM1 stimulates cell proliferation and cell …
Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis
CEP55 was initially identified as a pivotal component of abscission, the final stage of
cytokinesis, serving to regulate the physical separation of two daughter cells. Over the past …
cytokinesis, serving to regulate the physical separation of two daughter cells. Over the past …
SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma
YF Yang, MF Zhang, QH Tian, J Fu, X Yang, CZ Zhang… - Molecular cancer, 2018 - Springer
Background Deregulation of microtubules and centrosome integrity is response for the
initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is …
initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is …
Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation
F Qadir, MA Aziz, CP Sari, H Ma, H Dai, X Wang… - Molecular cancer, 2018 - Springer
Background Exosomes are extracellular vesicles released by almost all cell types, including
cancer cells, into bodily fluids such as saliva, plasma, breast milk, semen, urine …
cancer cells, into bodily fluids such as saliva, plasma, breast milk, semen, urine …
CEP 55 is a determinant of cell fate during perturbed mitosis in breast cancer
The centrosomal protein, CEP 55, is a key regulator of cytokinesis, and its overexpression is
linked to genomic instability, a hallmark of cancer. However, the mechanism by which it …
linked to genomic instability, a hallmark of cancer. However, the mechanism by which it …
Clinical significance of head and neck squamous cell cancer biomarkers
H Polanska, M Raudenska, J Gumulec… - Oral oncology, 2014 - Elsevier
Head and neck tumors belong among the six leading causes of cancer death worldwide.
The predominant type of head and neck tumors consists of squamous cell carcinomas …
The predominant type of head and neck tumors consists of squamous cell carcinomas …