Recent studies across multiple tumour types are starting to reveal a recurrent regulatory
architecture in which genomic alterations cluster upstream of functional master regulator …

The recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 causing
the respiratory tract disease COVID-19 has reached worldwide resonance and a global …

The renin-angiotensin system (RAS) is a network of proteins regulating many aspects of
human physiology, including cardiovascular, pulmonary, and immune system physiology …

Breast cancer is the cancer most often diagnosed in women. MicroRNAs (MIRs) are short
RNA molecules that bind mRNA resulting in their downregulation. MIR21 has been shown to …

Breast cancer is the neoplasm with the highest number of deaths in women. Although the
molecular mechanisms associated with the development of this tumor have been widely …

Over the last years, microRNAs (miRs) have shown to be crucial for breast tumour
establishment and progression. To understand the influence that miRs have over …

Objective To investigate the expression of targeting protein for Xenopus kinesin-like protein
2 (TPX2) in breast cancer tissue and to explore its role in proliferation, migration and …

Breast cancer is a heterogeneous and complex disease, a clear manifestation of this is its
classification into different molecular subtypes. On the other hand, gene transcriptional …

Master regulator genes (MRGs) have become a hot topic in recent decades. They not only
affect the development of tissue and organ systems but also play a role in other signal …

Breast cancer is a complex disease that is influenced by the concurrent influence of multiple
genetic and environmental factors. Recent advances in genomics and other high throughput …