Bone tissue renewal can be outlined as a complicated mechanism centered on the
interaction between osteogenic and angiogenic events capable of leading to bone formation …

Bone is a dynamic tissue constantly responding to environmental changes such as
nutritional and mechanical stress. Bone homeostasis in adult life is maintained through bone …

Skeletal elements have a diverse range of shapes and sizes specialized to their various
roles including protecting internal organs, locomotion, feeding, hearing, and vocalization …

Tissue engineering and its clinical application, regenerative medicine, are instructing
multiple approaches to aid in replacing bone loss after defects caused by trauma or cancer …

There is emerging interest in stem cell energy metabolism and its effect on differentiation.
Bioenergetic changes in differentiating bone marrow mesenchymal stem cells (MSCs) are …

Osteoblasts are the only cells that can give rise to bones in vertebrates. Thus, one of the
most important functions of these metabolically active cells is mineralized matrix production …

Human skeletal stem cells (SSCs) have been discovered in fetal and adult long bones.
However, the spatiotemporal ontogeny of human embryonic SSCs during early …

Vascularization is critical for skull development, maintenance, and healing. Yet, there
remains a significant knowledge gap in the relationship of blood vessels to cranial skeletal …

Cranial sutures are major growth centers for the calvarial vault, and their premature fusion
leads to a pathologic condition called craniosynostosis. This study investigates whether …

Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe, debilitating
condition affecting patients with cancer and patients with osteoporosis who have been …