Origin and function of the yolk sac in primate embryogenesis
C Ross, TE Boroviak - Nature communications, 2020 - nature.com
Human embryogenesis is hallmarked by two phases of yolk sac development. The primate
hypoblast gives rise to a transient primary yolk sac, which is rapidly superseded by a …
hypoblast gives rise to a transient primary yolk sac, which is rapidly superseded by a …
The primitive streak and cellular principles of building an amniote body through gastrulation
BACKGROUND Pluripotent cells are generated by embryonic divisions that occur shortly
after fertilization. These cells are transformed into the recognizable outline of an organism …
after fertilization. These cells are transformed into the recognizable outline of an organism …
Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering
Gastrulation is a fundamental and critical process of animal development whereby the mass
of cells that results from the proliferation of the zygote transforms itself into a recognizable …
of cells that results from the proliferation of the zygote transforms itself into a recognizable …
A hexa-species transcriptome atlas of mammalian embryogenesis delineates metabolic regulation across three different implantation modes
A Malkowska, C Penfold, S Bergmann… - Nature …, 2022 - nature.com
Mammalian embryogenesis relies on glycolysis and oxidative phosphorylation to balance
the generation of biomass with energy production. However, the dynamics of metabolic …
the generation of biomass with energy production. However, the dynamics of metabolic …
Alternative mammalian strategies leading towards gastrulation: losing polar trophoblast (Rauber's layer) or gaining an epiblast cavity
PL Pfeffer - … Transactions of the Royal Society B, 2022 - royalsocietypublishing.org
Using embryological data from 14 mammalian orders, the hypothesis is presented that in
placental mammals, epiblast cavitation and polar trophoblast loss are alternative …
placental mammals, epiblast cavitation and polar trophoblast loss are alternative …
The hypoblast (visceral endoderm): an evo-devo perspective
CD Stern, KM Downs - Development, 2012 - journals.biologists.com
When amniotes appeared during evolution, embryos freed themselves from intracellular
nutrition; development slowed, the mid-blastula transition was lost and maternal …
nutrition; development slowed, the mid-blastula transition was lost and maternal …
Conserved features of non-primate bilaminar disc embryos and the germline
Post-implantation embryo development commences with a bilaminar disc in most mammals,
including humans. Whereas access to early human embryos is limited and subject to greater …
including humans. Whereas access to early human embryos is limited and subject to greater …
Major transcriptomic, epigenetic and metabolic changes underlie the pluripotency continuum in rabbit preimplantation embryos
W Bouchereau, L Jouneau, C Archilla, I Aksoy… - …, 2022 - journals.biologists.com
Despite the growing interest in the rabbit model for developmental and stem cell biology, the
characterization of embryos at the molecular level is still poorly documented. We conducted …
characterization of embryos at the molecular level is still poorly documented. We conducted …
Morphological and gene expression changes in cattle embryos from hatched blastocyst to early gastrulation stages after transfer of in vitro produced embryos
A detailed morphological staging system for cattle embryos at stages following blastocyst
hatching and preceding gastrulation is presented here together with spatiotemporal …
hatching and preceding gastrulation is presented here together with spatiotemporal …
Why machine-information metaphors are bad for science and science education
Genes are often described by biologists using metaphors derived from computational
science: they are thought of as carriers of information, as being the equivalent of “blueprints” …
science: they are thought of as carriers of information, as being the equivalent of “blueprints” …