Hyperosmotic tear stimulates human corneal nerve endings, activates ocular immune
response, and elicits dry-eye symptoms. A soft contact lens (SCL) covers the cornea …

The ocular lubrication, where the eyelid constantly slides on the curved corneal surface, is
considered as one of primary lubrication systems in bio-tribology. Under reliable lubrication …

To date, there have been no well-organized clinical studies evaluating which air pollutants
affect dry eye disease (DED). In this study, we investigated changes in the clinical …

Purpose To assess air pollution-induced changes on ocular surface and tear cytokine levels.
Methods As a prospective multicenter cohort study, 387 dry eye disease (DED) participants …

Dry eye symptoms are associated with refractive errors. We aimed to measure the tear
evaporation rate (TER) in subjects with refractive errors (RE) using a portable evaporimeter …

The aim of the study was to analyze the correlation between the presence of Demodex mites
in the hair follicles of patients' eyelashes and the stability and break up time of the tear film …

We propose an alternative to the prevailing framework for modelling tear-film breakup, which
posits a layered structure with a mucus layer next to the cornea and an aqueous layer on …

Mucin polymers in the tear film protect the corneal surface from pathogens and modulate the
tear-film flow characteristics. Recent studies have suggested a relationship between the loss …

Evaporation is a recognized contributor to tear film thinning and tear breakup (TBU).
Recently, a different type of TBU is observed, where TBU happens under or around a thick …

Current ophthalmological drug discovery and testing methods have limitations and concerns
regarding reliability, ethicality, and applicability. These drawbacks can be mitigated by …