[HTML][HTML] The roles of MicroRNA in lung cancer

KL Wu, YM Tsai, CT Lien, PL Kuo, JY Hung - International journal of …, 2019 - mdpi.com
Lung cancer is the most devastating malignancy in the world. Beyond genetic research,
epigenomic studies—especially investigations of microRNAs—have grown rapidly in …

Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

[HTML][HTML] A proteogenomic portrait of lung squamous cell carcinoma

S Satpathy, K Krug, PMJ Beltran, SR Savage, F Petralia… - Cell, 2021 - cell.com
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

JD Campbell, A Alexandrov, J Kim, J Wala, AH Berger… - Nature …, 2016 - nature.com
To compare lung adenocarcinoma (ADC) and lung squamous cell carcinoma (SqCC) and to
identify new drivers of lung carcinogenesis, we examined the exome sequences and copy …

Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non–small cell lung cancer using next-generation sequencing

X **, Y Chen, H Chen, S Fei, D Chen, X Cai… - Clinical cancer …, 2017 - aacrjournals.org
Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …

MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

MV Iorio, CM Croce - EMBO molecular medicine, 2012 - embopress.org
Early studies have shown how aberrantly expressed microRNAs are a hallmark of several
diseases like cancer. MicroRNA expression profiling was shown to be associated with …

[HTML][HTML] Progress of exosomes in the diagnosis and treatment of lung cancer

K Xu, C Zhang, T Du, ANA Gabriel, X Wang, X Li… - Biomedicine & …, 2021 - Elsevier
The incidence and mortality of lung cancer account for first place all over the world. Lung
cancer lacks early diagnostic biomarkers; lung cancer patients are usually diagnosed in …

microRNAs in cancer management

YW Kong, D Ferland-McCollough, TJ Jackson… - The lancet …, 2012 - thelancet.com
Since the identification of microRNAs (miRNAs) in 1993, and the subsequent discovery of
their highly conserved nature in 2000, the amount of research into their function …

[HTML][HTML] microRNAs derived from circulating exosomes as noninvasive biomarkers for screening and diagnosing lung cancer

R Cazzoli, F Buttitta, M Di Nicola, S Malatesta… - Journal of thoracic …, 2013 - Elsevier
Introduction: Lung cancer is the highest cause of mortality among tumor pathologies
worldwide. There are no validated techniques for an early detection of pulmonary cancer …

[HTML][HTML] Genetic alterations defining NSCLC subtypes and their therapeutic implications

LA Pikor, VR Ramnarine, S Lam, WL Lam - Lung cancer, 2013 - Elsevier
Lung cancer is the leading cause of cancer death worldwide, accounting for more deaths
than breast, prostate and colon cancer combined. While treatment decisions are determined …