[HTML][HTML] Comprehensive Approaches to Combatting Acinetobacter baumannii Biofilms: From Biofilm Structure to Phage-Based Therapies

I Grygiel, O Bajrak, M Wójcicki, K Krusiec… - Antibiotics, 2024 - mdpi.com
Acinetobacter baumannii—a multidrug-resistant (MDR) pathogen that causes, for example,
skin and soft tissue wounds; urinary tract infections; pneumonia; bacteremia; and …

Comparative genomics of Acinetobacter baumannii and therapeutic bacteriophages from a patient undergoing phage therapy

M Liu, A Hernandez-Morales, J Clark, T Le… - Nature …, 2022 - nature.com
Abstract In 2016, a 68-year-old patient with a disseminated multidrug-resistant Acinetobacter
baumannii infection was successfully treated using lytic bacteriophages. Here we report the …

[HTML][HTML] Acinetobacter baumannii: More ways to die

GK Oyejobi, SO Olaniyan, NA Yusuf… - Microbiological …, 2022 - Elsevier
Acinetobacter baumannii is an important nosocomial and opportunistic pathogen. It causes
infections worldwide, especially in intensive care units. It is clinically significant owing to its …

Characterization of a novel and active temperate phage vB_AbaM_ABMM1 with antibacterial activity against Acinetobacter baumannii infection

M Mardiana, SH Teh, YC Tsai, HH Yang, LC Lin… - Scientific Reports, 2023 - nature.com
Acinetobacter baumannii is an opportunistic pathogen that significantly causes hospital-
acquired infections. Due to its multidrug resistance, treating infections caused by this …

Friunavirus Phage-Encoded Depolymerases Specific to Different Capsular Types of Acinetobacter baumannii

OY Timoshina, AA Kasimova, MM Shneider… - International Journal of …, 2023 - mdpi.com
Acinetobacter baumannii is a critical priority nosocomial pathogen that produces a variety of
capsular polysaccharides (CPSs), the primary receptors for specific depolymerase-carrying …

Loss of a Branch Sugar in the Acinetobacter baumannii K3-Type Capsular Polysaccharide Due To Frameshifts in the gtr6 Glycosyltransferase Gene Leads To …

OY Timoshina, AA Kasimova, MM Shneider… - Microbiology …, 2023 - Am Soc Microbiol
The type of capsular polysaccharide (CPS) on the cell surface of Acinetobacter baumannii
can determine the specificity of lytic bacteriophage under consideration for therapeutic use …

Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages

N Bagińska, MA Harhala, M Cieślik, F Orwat… - Viruses, 2023 - mdpi.com
Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a
serious threat today, which is aggravated by the growing problem of multi-drug resistance …

Host population structure and species resolution reveal prophage transmission dynamics

K Tenorio-Carnalla, A Aguilar-Vera… - MBio, 2024 - journals.asm.org
Much knowledge about bacteriophages has been obtained via genomics and
metagenomics over the last decades. However, most studies dealing with prophage …

Phage therapy combats pandrug-resistant Acinetobacter baumannii infection safely and efficiently

WX Wang, JZ Wu, BL Zhang, JY Yu, LM Han… - International Journal of …, 2024 - Elsevier
Phage therapy offers a promising approach to combat the growing threat of antimicrobial
resistance. Yet, key questions remain regarding dosage, administration routes, combination …

Whole-Genome Analysis Reveals That Bacteriophages Promote Environmental Adaptation of Staphylococcus aureus via Gene Exchange, Acquisition, and Loss

W Zhou, H Wen, Y Li, Y Gao, X Zheng, L Yuan, G Zhu… - Viruses, 2022 - mdpi.com
The study of bacteriophages is experiencing a resurgence owing to their antibacterial
efficacy, lack of side effects, and low production cost. Nonetheless, the interactions between …