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The cellular and molecular basis of major depressive disorder: towards a unified model for understanding clinical depression
E Pitsillou, SM Bresnehan, EA Kagarakis… - Molecular biology …, 2020 - Springer
Major depressive disorder (MDD) is considered a serious public health issue that adversely
impacts an individual's quality of life and contributes significantly to the global burden of …
impacts an individual's quality of life and contributes significantly to the global burden of …
The ABCs of depression: integrating affective, biological, and cognitive models to explain the emergence of the gender difference in depression.
In adulthood, twice as many women as men are depressed, a pattern that holds in most
nations. In childhood, girls are no more depressed than boys, but more girls than boys are …
nations. In childhood, girls are no more depressed than boys, but more girls than boys are …
Neural mechanisms of genetic risk for impulsivity and violence in humans
Neurobiological factors contributing to violence in humans remain poorly understood. One
approach to this question is examining allelic variation in the X-linked monoamine oxidase A …
approach to this question is examining allelic variation in the X-linked monoamine oxidase A …
The role of monoamine oxidase enzymes in the pathophysiology of neurological disorders
Monoamine oxidase enzymes are responsible for the degredation of serotonin, dopamine,
and norepinephrine in the central neurvous system. Although it has been nearly 100 years …
and norepinephrine in the central neurvous system. Although it has been nearly 100 years …
Poor replication of candidate genes for major depressive disorder using genome-wide association data
FJ Bosker, CA Hartman, IM Nolte, BP Prins… - Molecular …, 2011 - nature.com
Abstract Data from the Genetic Association Information Network (GAIN) genome-wide
association study (GWAS) in major depressive disorder (MDD) were used to explore …
association study (GWAS) in major depressive disorder (MDD) were used to explore …
Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
This systematic review summarizes pharmacogenetic studies on antidepressant response
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …
and side effects. Out of the 17 genes we reviewed, 8 genes were entered into the meta …
Meta-analyses of genetic studies on major depressive disorder
The genetic basis of major depressive disorder (MDD) has been investigated extensively,
but the identification of MDD genes has been hampered by conflicting results from …
but the identification of MDD genes has been hampered by conflicting results from …
Multifinality in the development of personality disorders: A Biology× Sex× Environment interaction model of antisocial and borderline traits
Although antisocial personality disorder (ASPD) is more common among males and
borderline PD (BPD) is more common among females, some authors have suggested that …
borderline PD (BPD) is more common among females, some authors have suggested that …
Type A monoamine oxidase and serotonin are coordinately involved in depressive disorders: from neurotransmitter imbalance to impaired neurogenesis
M Naoi, W Maruyama, M Shamoto-Nagai - Journal of Neural Transmission, 2018 - Springer
Type A monoamine oxidase (MAOA) catabolizes monoamine transmitters, serotonin,
norepinephrine and dopamine, and plays a major role in the onset, progression and therapy …
norepinephrine and dopamine, and plays a major role in the onset, progression and therapy …
Pharmacogenetics of antidepressant response
Personalized medicine—the adaptation of therapies based on an individual's genetic and
molecular profile—is one of the most promising aspects of modern medicine. The …
molecular profile—is one of the most promising aspects of modern medicine. The …