The effect of the bacterial heat-stable nucleoid-structuring (H-NS) protein on gene
expression is overwhelmingly negative and extends throughout the genome, pointing to an …

DNA in bacterial chromosomes is organized into higher‐order structures by DNA‐binding
proteins called nucleoid‐associated proteins (NAPs) or bacterial chromatin proteins (BCPs) …

In all living cells, genomic DNA is compacted through interactions with dedicated proteins
and/or the formation of plectonemic coils. In bacteria, DNA compaction is achieved …

How genomes are organized within cells and how the 3D architecture of a genome
influences cellular functions are significant questions in biology. A bacterial genomic DNA …

Horizontal gene transfer plays a major role in microbial evolution. However, newly acquired
sequences can decrease fitness unless integrated into preexisting regulatory networks. We …

Histone-like nucleoid structuring protein (H-NS) is a modular protein that is associated with
the bacterial nucleoid. We used chromatin immunoprecipitation to determine the binding …

The crystalline state is considered to be incompatible with life. However, in living systems
exposed to severe environmental assaults, the sequestration of vital macromolecules in …

The bacterial chromosomal DNA is folded into a compact structure called nucleoid. The
shape and size of this 'body'is determined by a number of factors. Major players are DNA …

H‐NS is a small chromatin‐associated protein found in enterobacteria. H‐NS has affinity for
all types of nucleic acids but binds preferentially to intrinsically curved DNA. The major role …

H-NS and Lsr2 are nucleoid-associated proteins from Gram-negative bacteria and
Mycobacteria, respectively, that play an important role in the silencing of horizontally …