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Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
Evolution and neutralization escape of the SARS-CoV-2 BA. 2.86 subvariant
Abstract Omicron BA. 2.86 subvariant differs from Omicron BA. 2 as well as recently
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
circulating variants by over 30 mutations in the spike protein alone. Here we report on the …
Omicron BA. 4/BA. 5 escape neutralizing immunity elicited by BA. 1 infection
Abstract SARS-CoV-2 Omicron (B. 1.1. 529) BA. 4 and BA. 5 sub-lineages, first detected in
South Africa, have changes relative to Omicron BA. 1 including substitutions in the spike …
South Africa, have changes relative to Omicron BA. 1 including substitutions in the spike …
SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape
Characterizing SARS-CoV-2 evolution in specific geographies may help predict properties
of the variants that come from these regions. We mapped neutralization of a SARS-CoV-2 …
of the variants that come from these regions. We mapped neutralization of a SARS-CoV-2 …
Systematic review and meta-analyses of the interaction between HIV infection and COVID-19: two years' evidence summary
Introduction During the COVID-19 pandemic, people living with HIV (PLWH) were
considered to be at risk of worse COVID-19 outcomes once infected. However, the existing …
considered to be at risk of worse COVID-19 outcomes once infected. However, the existing …
[HTML][HTML] Emergence of new SARS-CoV-2 Variant of Concern Omicron (B. 1.1. 529)-highlights Africa's research capabilities, but exposes major knowledge gaps …
E Petersen, F Ntoumi, DS Hui, A Abubakar… - International Journal of …, 2022 - Elsevier
Nearly two years since the start of the SARS-CoV-2 pandemic, which has caused over 5
million deaths, the world continues to be on high COVID-19 alert. The World Health …
million deaths, the world continues to be on high COVID-19 alert. The World Health …
Global and regional prevalence and outcomes of COVID-19 in people living with HIV: a systematic review and meta-analysis
Background: The relationship between HIV (human immunodeficiency virus) and COVID-19
clinical outcome is uncertain, with conflicting data and hypotheses. We aimed to assess the …
clinical outcome is uncertain, with conflicting data and hypotheses. We aimed to assess the …
Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition
T Nkosi, C Chasara, AO Papadopoulos, TL Nguni… - Elife, 2022 - elifesciences.org
In some instances, unsuppressed HIV has been associated with severe COVID-19 disease,
but the mechanisms underpinning this susceptibility are still unclear. Here, we assessed the …
but the mechanisms underpinning this susceptibility are still unclear. Here, we assessed the …
The consequences of SARS-CoV-2 within-host persistence
SARS-CoV-2 causes an acute respiratory tract infection that resolves in most people in less
than a month. Yet some people with severely weakened immune systems fail to clear the …
than a month. Yet some people with severely weakened immune systems fail to clear the …
Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease
A Allué-Guardia, JB Torrelles, A Sigal - Frontiers in Immunology, 2023 - frontiersin.org
Mycobacterium tuberculosis (M. tb) and SARS-CoV-2 are both infections that can lead to
severe disease in the lower lung. However, these two infections are caused by very different …
severe disease in the lower lung. However, these two infections are caused by very different …