Synucleinopathies are neurodegenerative disorders characterized by alpha-synuclein
(αSyn) accumulation in neurons or glial cells, including Parkinson's disease (PD), dementia …

Disease modeling in non-human subjects is an essential part of any clinical research. To
gain proper understanding of the etiology and pathophysiology of any disease, experimental …

The pedunculopontine nucleus (PPN) is a locomotor command area containing
glutamatergic neurons that control locomotor initiation and maintenance. These motor …

Parkinson's disease (PD) is a prevalent movement disorder characterized by the
progressive loss of dopaminergic neurons in substantia nigra pars compacta (SNpc). The 6 …

Excessive daytime sleepiness (EDS) and sleep fragmentation are often observed in
Parkinson's disease (PD) patients and are poorly understood despite their considerable …

Abstract Parkinson's disease (PD), a neurodegenerative disorder, is one of the most
significant challenges confronting modern societies, affecting millions of patients globally …

Background: Recent studies have revealed the close correlation between microRNAs
(miRs) and Parkinson's disease (PD). Here, we aimed to investigate the neuroprotective …

Recent advanced studies in neurodegenerative diseases have revealed several links
connecting autophagy and neurodegeneration. Autophagy is the major cellular degradation …

Parkinson's disease (PD) is characterized by motor impairments caused by degeneration of
dopamine neurons in the substantia nigra pars compacta. In addition to these symptoms, PD …

Motor symptoms of Parkinson's disease (PD)-bradykinesia, akinesia, and tremor at rest-are
consequences of the neurodegeneration of dopaminergic neurons in the substantia nigra …