Ape origins of human malaria
PM Sharp, LJ Plenderleith… - Annual review of …, 2020 - annualreviews.org
African apes harbor at least twelve Plasmodium species, some of which have been a source
of human infection. It is now well established that Plasmodium falciparum emerged following …
of human infection. It is now well established that Plasmodium falciparum emerged following …
Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics
C Bourgard, L Albrecht, ACAV Kayano… - Frontiers in cellular …, 2018 - frontiersin.org
During the last decade, the vast omics field has revolutionized biological research,
especially the genomics, transcriptomics and proteomics branches, as technological tools …
especially the genomics, transcriptomics and proteomics branches, as technological tools …
Malaria protection due to sickle haemoglobin depends on parasite genotype
G Band, EM Leffler, M Jallow, F Sisay-Joof, CM Ndila… - Nature, 2022 - nature.com
Host genetic factors can confer resistance against malaria, raising the question of whether
this has led to evolutionary adaptation of parasite populations. Here we searched for …
this has led to evolutionary adaptation of parasite populations. Here we searched for …
Extreme mutation bias and high AT content in Plasmodium falciparum
For reasons that remain unknown, the Plasmodium falciparum genome has an exceptionally
high AT content compared to other Plasmodium species and eukaryotes in general-nearly …
high AT content compared to other Plasmodium species and eukaryotes in general-nearly …
THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites
As many malaria-endemic countries move towards elimination of Plasmodium falciparum,
the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology …
the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology …
Map** imported malaria in Bangladesh using parasite genetic and human mobility data
For countries aiming for malaria elimination, travel of infected individuals between endemic
areas undermines local interventions. Quantifying parasite importation has therefore …
areas undermines local interventions. Quantifying parasite importation has therefore …
Map** malaria by combining parasite genomic and epidemiologic data
Background Recent global progress in scaling up malaria control interventions has revived
the goal of complete elimination in many countries. Decreasing transmission intensity …
the goal of complete elimination in many countries. Decreasing transmission intensity …
Genome-Wide Analysis of Selection on the Malaria Parasite Plasmodium falciparum in West African Populations of Differing Infection Endemicity
Locally varying selection on pathogens may be due to differences in drug pressure, host
immunity, transmission opportunities between hosts, or the intensity of between-genotype …
immunity, transmission opportunities between hosts, or the intensity of between-genotype …
Population parameters underlying an ongoing soft sweep in Southeast Asian malaria parasites
TJC Anderson, S Nair, M McDew-White… - Molecular biology …, 2017 - academic.oup.com
Multiple kelch13 alleles conferring artemisinin resistance (ART-R) are currently spreading
through Southeast Asian malaria parasite populations, providing a unique opportunity to …
through Southeast Asian malaria parasite populations, providing a unique opportunity to …
Evolutionary history of human Plasmodium vivax revealed by genome-wide analyses of related ape parasites
DE Loy, LJ Plenderleith… - Proceedings of the …, 2018 - National Acad Sciences
Wild-living African apes are endemically infected with parasites that are closely related to
human Plasmodium vivax, a leading cause of malaria outside Africa. This finding suggests …
human Plasmodium vivax, a leading cause of malaria outside Africa. This finding suggests …