Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Stem cell therapy is widely recognized as a promising strategy for exerting therapeutic
effects after injury in degenerative diseases. However, limitations such as low cell retention …

The chemistry, geometry, topography and mechanical properties of biomaterials modulate
biochemical signals (in particular ligand-receptor binding events) that control cells-matrix …

This Review presents an overview of recent development of colloidal lithography (CL) and
its applications in fabrication of various nanostructures consisted of orderly arranged, dots …

Control over biointerfacial interactions in vitro and in vivo is the key to many biomedical
applications: from cell culture and diagnostic tools to drug delivery, biomaterials and …

The chemical composition of the surface layers of synthetic biomaterials used for human
medical devices and in biotechnology plays a key role in determining interfacial interactions …

We show that the nanoscale adhesion geometry controls the spreading and differentiation of
epidermal stem cells. We find that cells respond to such hard nanopatterns similarly to their …

We have established long-term cultures of postnatal retinal cells on arrays of gallium
phosphide nanowires of different geometries. Rod and cone photoreceptors, ganglion cells …

Background Cells explore the surfaces of materials through membrane-bound receptors,
such as the integrins, and use them to interact with extracellular matrix molecules adsorbed …

Surfaces of implantable biomedical devices are increasingly engineered to promote their
interactions with tissue. However, surfaces that stimulate desirable mammalian cell …