Novel therapeutic strategies: targeting epithelial–mesenchymal transition in colorectal cancer

N Zhang, AS Ng, S Cai, Q Li, L Yang, D Kerr - The Lancet Oncology, 2021 - thelancet.com
Epithelial–mesenchymal transition (EMT) is a process during which cells lose their epithelial
characteristics, for instance apical–basal cell polarity and cell–cell contact, and gain …

Tensegrity I. Cell structure and hierarchical systems biology

DE Ingber - Journal of cell science, 2003 - journals.biologists.com
In 1993, a Commentary in this journal described how a simple mechanical model of cell
structure based on tensegrity architecture can help to explain how cell shape, movement …

Vimentin filaments integrate low-complexity domains in a complex helical structure

M Eibauer, MS Weber, R Kronenberg-Tenga… - Nature Structural & …, 2024 - nature.com
Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells
with tissue-specific mechanical properties and are involved in numerous cellular processes …

[HTML][HTML] Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition

MG Mendez, SI Kojima, RD Goldman - The FASEB Journal, 2010 - pmc.ncbi.nlm.nih.gov
Vimentin is used widely as a marker of the epithelial to mesenchymal transitions (EMTs) that
take place during embryogenesis and metastasis, yet the functional implications of the …

[HTML][HTML] Vimentin intermediate filaments template microtubule networks to enhance persistence in cell polarity and directed migration

Z Gan, L Ding, CJ Burckhardt, J Lowery, A Zaritsky… - Cell systems, 2016 - cell.com
Increased expression of vimentin intermediate filaments (VIFs) enhances directed cell
migration, but the mechanism behind VIFs' effect on motility is not understood. VIFs interact …

[หนังสือ][B] Cell movements: from molecules to motility

D Bray - 2000 - taylorfrancis.com
Cell Movements vividly describes how complex movements can arise from the properties
and behaviors of biological molecules. This second edition is updated throughout with …

Chitosan‑sodium alginate-collagen/gelatin three-dimensional edible scaffolds for building a structured model for cell cultured meat

L Li, L Chen, X Chen, Y Chen, S Ding, X Fan… - International Journal of …, 2022 - Elsevier
Cell cultured meat (CCM) production is an innovative technology that does not depend on
livestock farming practices to produce meat. The construction of structured CCM requires a …

Intermediate filaments: from cell architecture to nanomechanics

H Herrmann, H Bär, L Kreplak, SV Strelkov… - … reviews Molecular cell …, 2007 - nature.com
Intermediate filaments (IFs) constitute a major structural element of animal cells. They build
two distinct systems, one in the nucleus and one in the cytoplasm. In both cases, their major …

Cytoskeletal regulation of pulmonary vascular permeability

SM Dudek, JGN Garcia - Journal of applied physiology, 2001 - journals.physiology.org
The endothelial cell (EC) lining of the pulmonary vasculature forms a semipermeable barrier
between the blood and the interstitium of the lung. Disruption of this barrier occurs during …

A structural scaffolding of intermediate filaments in health and disease

E Fuchs, DW Cleveland - Science, 1998 - science.org
The cytoplasm of animal cells is structured by a scaffolding composed of actin
microfilaments, microtubules, and intermediate filaments. Intermediate filaments, so named …