Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

[HTML][HTML] Microsponges for dermatological applications: Perspectives and challenges

S Mahant, S Kumar, S Nanda, R Rao - Asian journal of pharmaceutical …, 2020 - Elsevier
Dermatological disorders have a huge psychosocial impact, causing significant impairment
of patient's life. Topical therapy plays a pivotal role in management of such disorders …

[HTML][HTML] QBD approach for the development of hesperetin loaded colloidal nanosponges for sustained delivery: In-vitro, ex-vivo, and in-vivo assessment

K Rodrigues, S Nadaf, N Rarokar, N Gurav, P Jagtap… - OpenNano, 2022 - Elsevier
Hesperetin (HT) is a polyphenolic compound with anti-carcinogenic, tumor necrosis, and
anti-oxidant properties. The present study reports the fabrication, optimization, and …

Microsponge: an emerging drug delivery strategy

G Singhvi, P Manchanda, N Hans… - Drug development …, 2019 - Wiley Online Library
Microsponges are the spherical particles ranging from 5 to 300 μm in size. These are further
made up of clusters of smaller spheres. They are designed for delivering the drug efficiently …

Quality by design guided development of polymeric nanospheres of terbinafine hydrochloride for topical treatment of onychomycosis using a nano-gel formulation

V Puri, A Froelich, P Shah, S Pringle, K Chen… - Pharmaceutics, 2022 - mdpi.com
Superficial fungal diseases of the skin and nails are an increasingly common occurrence
globally, requiring effective topical treatment to avoid systemic adverse effects. Polymeric …

Dendrimer entrapped microsponge gel of dithranol for effective topical treatment

PK Tripathi, B Gorain, H Choudhury, A Srivastava… - Heliyon, 2019 - cell.com
Dithranol is one of the important topical agents for the treatment of psoriasis, a chronic
inflammatory skin disease with aberrant differentiation of keratinocytes. However, its …

Eudragit S100 coated microsponges for Colon targeting of prednisolone

A Kumari, A Jain, P Hurkat, A Tiwari… - Drug development and …, 2018 - Taylor & Francis
Context: Microsponge is a novel approach for targeting the drug to the colon for the
management of colon ailments such as inflammatory bowel disease. Objective …

Linalool-Incorporated Synergistically Engineered Modified Liposomal Nanocarriers for Enhanced Transungual Delivery of Terbinafine against Onychomycosis

I Gupta, SN Adin, MA Rashid, Y Alhamhoom, M Aqil… - Materials, 2023 - mdpi.com
This work investigates the synthesis of linalool-containing invasomes for terbinafine (TBF-IN)
in order to increase the solubility, bioavailability, and nail permeability of terbinafine (TBF) …

[HTML][HTML] Enhancing topical pharmacotherapy for acne and rosacea: vehicle choices and outcomes

LJ Green, E Lain, T Prunty… - The Journal of clinical and …, 2022 - ncbi.nlm.nih.gov
The choice of vehicle is an important consideration in the treatment of acne and rosacea.
Agents used to treat these common conditions may be limited by multiple factors, including …

Sponge particulates for biomedical applications: Biofunctionalization, multi-drug shielding, and theranostic applications

H Zhang, Y **, C Chi, G Han, W Jiang, Z Wang… - Biomaterials, 2021 - Elsevier
Sponge particulates have attracted enormous attention in biomedical applications for
superior properties, including large porosity, elastic deformation, capillary action, and three …